2) c) iii) Reversible Binding of Phosphate

Question 1

addition or removal of a phosphate causes?

Answer 1

The addition or removal of phosphate can cause reversible conformational change in proteins

Question 2

The addition or removal of a phosphate is?

Answer 2

This is a common form of post-translational modification

Question 3

What enzyme is responsible for transfer of a phosphate to another protein

Answer 3

Protein kinases catalyse the transfer of a
phosphate group to other proteins

Answer 4

The terminal phosphate of ATP is transferred to specific R groups

Question 5

What protein is responsible for the reverse reaction? What

Answer 5

Protein phosphatases catalyse the reverse reaction

Question 6

What does phosphorylation do?

Answer 6

Phosphorylation brings about conformational changes, which can affect a protein’s activity

Answer 7

The activity of many cellular proteins, such as enzymes and receptors, is regulated in this way

Answer 8

Some proteins are activated by
phosphorylation while others are inhibited

Question 9

addition of a phosphate adds what charge?

Answer 9

Adding a phosphate group adds negative
charges. Ionic interactions in the
unphosphorylated protein can be disrupted and new ones created.