Diltiazem HCL

Question 1

Diltiazem: Class

Answer 1

Calcium Channel Blocker

Question 2

Diltiazem: Mechanism of Action

Answer 2

• Block influx of calcium ions into cardiac muscle: prevents spasm of coronary arteries.
• Arterial and venous vasodilator.
• Reduces preload and afterload.
• Reduces myocardial oxygen demand.

Question 3

Diltiazem: Indications

Answer 3

• Control of rapid ventricular rates due to atrial flutter, atrial fibrillation, PSVT.
• Angina pectoris.

Question 4

Diltiazem: Adult Dose

Answer 4

• Initial bolus: 0.25 mg/ kg (average dose 20 mg) IV over two minutes.
• If inadequate response, may re-bolus in 15 minutes: 0.35 mg / kg IV over two (2) minutes.
• Maintenance infusion of 5-15 mg / hour.

Question 5

Diltiazem: Pediatric Dose

Answer 5

Not Recommended