Metoprolol

Question 1

Metoprolol Class:

Answer 1

Antianginal
Antihypertensive Agent
Beta Blocker

Question 2

Metoprolol Mechanism of Action:

Answer 2

• Selective inhibitor of beta 1-adrenergic receptors

- Completely blocks beta 1 receptors , with little or no effect on beta 2 receptors at doses <100 mg

Question 3

Metoprolol Indications:

Answer 3

• Treatment of hypertension and angina pectoris
• Prevention of myocardial infarction, atrial fibrillation, flutter -Symptomatic treatment of hypertrophic subaortic stenosis to reduce increased sympathetic stimuli in acute MI.

Question 4

Metoprolol Adult Dose:

Answer 4

• Hypertension: Has been given in dosages 1.25-5 mg every 6-12 hours in patients unable to take oral medications
• Myocardial infarction (acute): I.V. 5 mg every 5-10 minutes up to 3 doses in early treatment of myocardial infarction.

Question 5

Metoprolol Pediatric Dose:

Answer 5

Not recommended in pediatric population. The safety and effectiveness of Metoprolol have not been established in children