Nitroglycerine

Question 1

Nitroglycerine Class:

Answer 1

Vasodilator

Question 2

Nitroglycerine Mechanism of Action:

Answer 2

• Smooth muscle relaxant acting on vascular, bronchial, uterine and intestinal smooth muscle.
• Dilation of arterioles and veins in the periphery reduces preload and afterload, decreases the work load of the heart and, thereby, myocardial oxygen demand.

Question 3

Nitroglycerine Indications:

Answer 3

• Acute angina pectoris
• Ischemic chest pain
• Hypertension
• CHF
• Pulmonary edema

Question 4

Nitroglycerine Adult Dose:

Answer 4

• Tablets: 0.3 - 0.4 mg SL; may repeat in 3-5 minutes to maximum of 3 doses.
• Spray: 0.4 mg under the tongue; 1-3 sprays.
• IV infusion: 5 mcg / min.; increase by 5-10 mcg / min. every 5 minutes until desired effect.

Question 5

Nitroglycerine Pediatric Dose:

Answer 5

Not Recommended