Glucagon

Question 1

Glucagon Class:

Answer 1

Hyperglycemic agent, pancreatic hormone, insulin antagonist

Question 2

Glucagon Mechanism of Action:

Answer 2

• Increases blood glucose by stimulating glycolysis.
• Unknown mechanism of stabilizing cardiac rhythm in beta-blocker overdose.
• Minimal positive inotrope and chronotrope.
• Decreases GI motility and secretions.

Question 3

Glucagon Indications:

Answer 3

• Altered level of consciousness when hypoglycemia is suspected.
• May be used as inotropic agent in beta-blocker overdose.

Question 4

Glucagon Adult Dose:

Answer 4

0.5 - 1 mg IM, SC, or slow IV; may repeat q 20 minutes PRN.

Question 5

Glucagon Pediatric Dose:

Answer 5

0.03 - 0.1 mg / kg / dose (not to exceed 1 mg) q 20 min. IM, IO, SC, slow IV.