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Anatomic Pathology > More AP > Flashcards

More AP Flashcards

1
Q

Necrotizing sialometaplasia

A

mimics CA
Squamous metaplasia of ducts
lobular configuration

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2
Q

IHC of clear cell hyalinizing carcinoma

A

CEA+, P63+

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3
Q

IHC and nuclear features of polymorphous low grade carcinoma

A

S100+, open, vesicular nuclei

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4
Q

IHC for salivary duct CA

A

Androgen receptor+ Her2+

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5
Q

Painful salivary gland tumors

A

Adenoid cystic CA

Acinic cell CA

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6
Q

Infection assd with pulmonary malakoplakia

A

Rhodococcus equi

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7
Q

Pulmonary disorders with lymphangitic pattern

A

sarcoid
lymphoma
kaposi
langerhans

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8
Q

Pulmonary capillary hemangiomatosis

A

causes pulm htn

presents with hemoptysis

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9
Q

Dirofilariasis in the lung

A

Dead worms embolize from the heart to cause nodular infarcts with eosinophils

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10
Q

Diffuse panbronchiolitis

A

Interstitial foamy macrophages
Bronchiolocentric acute and chronic inflammation
Japanese

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11
Q

Alveolar adenoma

A

Multicystic proliferations

Cysts with epithelial lining and mesenchymal cell prolif

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12
Q

Congenital lobar emphysema

A

infants

caused by partial obstruction of bronchus

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13
Q

Placental transmogrification

A

lung parenchyma that looks like chorionic villi

seen in Giant Bullous Emphysema

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14
Q

Most common mesenchymal tumor os the liver in children

A

infantile hemangioendothelioma

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15
Q

“hypermature” chorionic villi assd with

A

uteroplacental insufficiency (ex. pre-eclampsis)

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16
Q

Liver features in pts with AP polycystic kidney dz

A

fibrosis around portal tracts

dilation of bile ducts (ductal plate malformation

17
Q

Salivary gland tumor with defining translocation

A

Mammary analog secretory CA

t(12;15) ETV6-NTRK3

18
Q

Variant of PTC with squamous metaplasia

A

Diffuse sclerosing PTC

19
Q

Variant of PTC assd with FAP

A

Cribriform morular variant

beta-catenin +

20
Q

Genetic alteration seen in PTC assd with radiation

A

RET/PTC translocation

21
Q

Most common genetic alteration in PTC

A

BRAF 7q23

22
Q

Genetics of follicular lesiosn

A

PAX8/PPAR-gamma

23
Q

Primary brain tumor that can metastasize to liver and lungs

A

gliosarcoma

24
Q

Tumor other than meningioma with “dura tail sign”

A

Desmoplastic infantile astrocytoma/gangliocytoma

25
Q

Two syndromes assd with medulloblastoma

A

Gorlin (Sonic-Hedgehog pathway)

Turcot (APC gene, WNT pathway)

26
Q

Desmoplastic medulloblastoma mutation

A

patched gene, sonic-hedgehog pathway

Anatomic Pathology (15 decks)

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