GI Path

Question 1

Sign that MALT lymphoma is less likely to respond to abx

Answer 1

t(11;18)

Question 2

Type of gastritis with, pernicious anemia, increased serum gastrin and assd carcinoids

Answer 2

Gastritis Type A

Question 3

H.Pylori assd gastritis

Answer 3

Gastritis Type B

Question 4

Infections assd with Menetrier dz

Answer 4

H. pylori and CMV

Question 5

Risk of dysplasia in FAP assd fundic gland polyps

Answer 5

up to 40%

Question 6

Mutations assd with sporadic fundic gland polyps

Answer 6

Beta-catenin

Question 7

Peutz-Jeghers associations

Answer 7

STK gene, ch19
Pancreatic tumors
Adenoma malignum cervix
SCTAT
Sclerosing Sertoli cell tumor
Breast CA

Question 8

Benign lesion on the differential with GIST

Answer 8

Inflammatory fibroid polyp (inflammation and eosinophils

Question 9

Type 2 gastric carcinoids are assd with…

Answer 9

MEN 1 and 2

Question 10

Type 1 gastric carcinoids are assd with…

Answer 10

Type A gastritis

Question 11

Giardia prevalence

Answer 11

5%

Question 12

Follow-up method after tx for Whipple dz

Answer 12

PCR (PAS-D may still be +)

Question 13

Histology of strongyloides hyperinfection

Answer 13

Eos and crystals aorund filarial larvae, Splendore-Hoeppli

Question 14

Most sensitive and specific test for celiac

Answer 14

anti-tissue transglutaminase

Question 15

HLA types assd with celiac

Answer 15

DQ2 and DQ8

Question 16

Type of T-cells in epithelium of celiac

Answer 16

Gamma-delta

Question 17

What signals an increased risk of enteropathy assd T cell lymphoma in celiac

Answer 17

Loss of CD8 positivity

Question 18

GI histology of Waldenstrom

Answer 18

IgM deposition in small bowel lacteals

Question 19

GI histology of Abetalipoproteinemia

Answer 19

lipid globules in enterocytes of small bowel

Question 20

Aggressive carcinoid generally found in the appendix

Answer 20

goblet cell carcinoid (adenocarcinoid)

Question 21

Psammomatous somatistatinoma

Answer 21

only occurs at Ampulla of Vater

Assd with NF1

Question 22

“flask-shaped” ulcer in colon

Answer 22

amebiasis (may also see erythrophagocytosis)

Question 23

Spirochetosis histology

Answer 23

very thick layer on apex of mucosa

Question 24

Type of collagen in normal colon basement membrane and in collagenous colitis

Answer 24

Normal = Collagen IV

Collagenous colitis = Collagens I, III, VI, tenascin