Acetaminophen (Tylenol) Flashcards
1
Q
Drug Classification
A
Antipyretic/Analgesic
2
Q
Mechanism of Action
A
COX inhibitor ->elevation of pain threshold, antipyretic by action on hypothalamic heat regulatory center
3
Q
Pharmacokinetics
A
- Onset of Action- 15-30 minutes
- Peak Effects- 30-120 minutes
- Duration of Effects- 3-4 hours
- Half-Life- 1-3 hours
4
Q
Indications/Field Use
A
Pediatric Fever
5
Q
Contraindications
A
Hypersensitivity
6
Q
Side Effects/Adverse Reactions
A
Abdominal pain, dizziness, hypoglycemia, N&V
7
Q
Dose
A
Pedi:
15mg/kg PO q 4-6 hours PRN, max dose 4g/day
8
Q
Precautions
A
- Metabolized by liver- overdose can be toxic
- Doesn’t have anti-platelet aggregation effect
- Doesn’t have peripheral anti-inflammatory effects
9
Q
Drug-Drug Interactions
A
Chronic excessive use of alcohol increases risk of hepatotoxicity
10
Q
Toxic Dose
A
140mg/kg
Cut in half if pt has liver issues
