Genetics

Question 0

What are Mendels laws of inheritance?

Answer 0

1st law- law of segregation- each individual has two units of inheritance but only one is passed onto offspring

2nd law- law of independent assortment- genes at diff loci segregate independently

Question 0

What is non disjunction?

Answer 0

The result of non disjunction is the production of gametes that either lack a chromosome or have an additional one
Can happen in meiosis 1 or 2 but more common in women in 1

Question 1

Give two examples of autochromal recessive disorders?

Answer 1

Sickle cell

Systic fibrosis

Question 2

What’s the difference between aneuploid and euploid?

Answer 2

Cell with abnormal no of chromosomes = aneuploid

Cell with normal no of chromosomes = euploid

Question 3

Why do mutations occur?

Answer 3

Imperfect copying
Chemical damage
Radiation

Question 4

What are the different mutation types?

Answer 4

Deletion
Substitution
Insertion

Question 5

What is missense mutation?

Answer 5

Amino acid substitutions