Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

[Immunohematology] Lec > [25] CHAPTER X LESSON 3 > Flashcards

[25] CHAPTER X LESSON 3 Flashcards

1
Q

is the donation of blood by the intended recipient.

A

Autologous (self) transfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The infusion of blood from another donor is called

A

allogeneic transfusion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The patient’s own blood reduces the possibility of transfusion reaction or transmission of infectious disease

A

Autologous (self) transfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

 Collected by regular blood donation procedure, the blood can be stored as liquid or, for longer storage, frozen.

A
  1. Predeposit autologous donation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

 Usually reserved for patients anticipating a need for transfusion, such as for a scheduled surgery

A
  1. Predeposit autologous donation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

 Collection of 1 or 2 units of blood from the patient just before a surgical procedure, replacing the removed blood volume with crystalloid or colloid solution.

A
  1. Intraoperative hemodilution
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Then, at the end of surgery, the blood units are infused into the patient.

A
  1. Intraoperative hemodilution
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

 Group O RBCs are selected for patients for whom transfusion cannot wait until their ABO and Rh type can be determined.

A
  1. Emergency Transfusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

 Group O-negative RBC units should be used if the patient is a female of child-bearing potential.

A
  1. Emergency Transfusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

 After issuing O blood or type-specific blood, the antibody screen can be completed, and decisions can then be made for the selection of additional units of blood.

A
  1. Emergency Transfusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

 Massive transfusion is defined as the replacement of one or more blood volumes within 24 hours, or about 10 units of blood in an adult.

A
  1. Massive Transfusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Draw type and crossmatch

A

2 units group O RBCs uncrossmatched

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Prepare massive transfusion protocol pack by transfusion service

A

4 to 6 type-specific or cross matched RBCs
4 plasma
1 platelet pool or plateletpheresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Monitor CBC, platelet count, PT/INR, PTT, fibrinogen

A

Add or subtract components based on lab values

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Provide additional MTP packs

A

Continue transfusion until unneeded

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

 Premature infants frequently require transfusion of small amounts of RBCs to replace blood drawn for laboratory tests and to treat the anemia of prematurity

A
  1. Neonatal Transfusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Neonatal Transfusion
 A dose of [?] will increase the hemoglobin by approximately [?]

A

10 mL/kg

3 g/dL.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

 Neonatal Transfusion Aliquoted Units

A

 Less than 7 days old, unless infused slowly
 O-negative or compatible with mother and infant
 CMV-negative or leukocyte-reduced
 Hemoglobin S–negative for hypoxic newborns

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

 Neonatal Transfusion Dose:

A

10 mL/kg over 2 to 3 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

The patient identification label is compared at the bedside to the [?]. This prevents a specimen tube labeled with one patient’s name being used for the collection of a specimen from another patient.

A

patient’s hospital armband

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

The [?] are applied to the specimen tubes before leaving the bedside to avoid labeling the wrong tube.

A

labels

22
Q

The AABB Standards states “Blood and blood components shall be transfused through a [?] that has a filter designed to retain particles potentially harmful to the recipient.”

A

sterile, pyrogen-free transfusion set

23
Q

Blood components are infused slowly for the first [?] while the patient is observed closely for signs of a transfusion reaction.

A

10 to 15 minutes

24
Q

The blood components should then be infused as quickly as tolerated or, at most, within [?].

A

4 hours

25
Q

In standard blood administration sets, the [?] filter removes gross clots and cellular debris.

A

150- to 260-µm

26
Q

A [?] must be used for transfusion of all blood components.

A

blood administration filter

27
Q

• The receipt, preparation, and issue of blood components is guided by [?] published and enforced by the FDA.

A

current good manufacturing practice (cGMP) regulations

28
Q

• Each blood product is prepared and stored to optimize its [?] at the time of transfusion.

A

purity and potency

29
Q

• Quality control parameters are set by the [?].

A

FDA and AABB

30
Q

Increases red cell mass and plasma volume

A

Whole blood

31
Q

Whole blood Often available only for autologous units
Red Blood Cells (RBCs),
Apheresis RBCs
Increase oxygen-carrying capacity in anemia, trauma, and surgery
Expiration varies with anticoagulant
Frozen/deglycerolized RBCs
Prolonged red cell storage for rare blood units and autologous storage
24-hour outdate following deglycerolization
Washed RBCs
Reduce plasma proteins to avoid allergic and anaphylactic reactions (IgA deficiency)
24-hour expiration following washing
Platelets and RBCs Leukocyte
Reduced
Avoid febrile nonhemolytic reactions and prevent HLA alloimmunization, reduce
CMV transmission
Prestorage filtration more effective in avoiding cytokines
Irradiated RBCs and Platelets
Prevent GVHD in
immunocompromised patients, HLA-matched platelets or transfusions from a blood relative
Irradiation decreases shelf life of RBCs to 28 days
Platelets, Pooled Platelets
Bleeding caused by thrombocytopenia or thrombocytopathy
Pooling reduces expiration to 4
hours
Apheresis Platelets
Bleeding caused by thrombocytopenia or thrombocytopathy
May be HLA matched with recipient in cases of refractoriness
FFP, PF24
Replace stable and labile coagulation factors
Used in surgeries, trauma, and some factor deficiencies
Cryoprecipitated AHF (CRYO)
Contains fibrinogen, factors XIII and VIII, and von Willebrand’s factor
Treatment of von Willebrand’s disease, fibrinogen deficiency, and hemophilia A
Apheresis Granulocytes
Neutropenia with infection, unresponsive to antibiotics
Contains RBCs, must be ABO compatible

A
32
Q

Often available only for autologous units

A

Whole blood

33
Q

Increase oxygen-carrying capacity in anemia, trauma, and surgery

A

Red Blood Cells (RBCs), Apheresis RBCs

34
Q

Expiration varies with anticoagulant

A

Red Blood Cells (RBCs), Apheresis RBCs

35
Q

Prolonged red cell storage for rare blood units and autologous storage

A

Frozen/deglycerolized RBCs

36
Q

24-hour outdate following deglycerolization

A

Frozen/deglycerolized RBCs

37
Q

Reduce plasma proteins to avoid allergic and anaphylactic reactions (IgA deficiency)

A

Washed RBCs

38
Q

24-hour expiration following washing

A

Washed RBCs

39
Q

Avoid febrile nonhemolytic reactions and prevent HLA alloimmunization, reduce

A

Platelets and RBCs Leukocyte Reduced

40
Q

CMV transmission

A

Platelets and RBCs Leukocyte Reduced

41
Q

Prestorage filtration more effective in avoiding cytokines

A

Platelets and RBCs Leukocyte Reduced

42
Q

Prevent GVHD in immunocompromised patients, HLA-matched platelets or transfusions from a blood relative

A

Irradiated RBCs and Platelets

43
Q

Irradiation decreases shelf life of RBCs to 28 days

A

Irradiated RBCs and Platelets

44
Q

Bleeding caused by thrombocytopenia or thrombocytopathy

A

Platelets, Pooled Platelets

45
Q

Pooling reduces expiration to 4 hours

A

Platelets, Pooled Platelets

46
Q

Bleeding caused by thrombocytopenia or thrombocytopathy

A

Apheresis Platelets

47
Q

May be HLA matched with recipient in cases of refractoriness

A

Apheresis Platelets

48
Q

Replace stable and labile coagulation factors

A

FFP, PF24

49
Q

Used in surgeries, trauma, and some factor deficiencies

A

FFP, PF24

50
Q

Contains fibrinogen, factors XIII and VIII, and von Willebrand’s factor

A

Cryoprecipitated AHF (CRYO)

51
Q

Treatment of von Willebrand’s disease, fibrinogen deficiency, and hemophilia A

A

Cryoprecipitated AHF (CRYO)

52
Q

Neutropenia with infection, unresponsive to antibiotics

A

Apheresis Granulocytes

[Immunohematology] Lec (35 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions