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[Immunohematology] Lec > CHAP 10 SUMMARIZED > Flashcards

CHAP 10 SUMMARIZED Flashcards

1
Q

Labeling Requirements for Blood and Components
• (?) symbology
• (?) of product
• (?) of preparation (whole blood, apheresis)
• Storage (?)
• Preservatives/(?)
• (?) in pooled components
• (?) of collection & processing facility
• (?) (& time if applicable). When expiration time not indicated, expiration is at midnight.
• Identification number for unit or pool
• Donor category (volunteer, autologous)
• (?), if applicable.
• (?)information
• (?) regarding recipient identification, Circular of Information, infectious disease risk, & prescription requirement
• (?): “For Autologous Use Only.”
Biohazard label if any infectious disease markers are pos or “Donor Untested” if testing not performed.

A

ISBT 128 bar-code

Name

Method

temperature

anticoagulant

Number of units

Name, address, registration number, & license number

Expiration date

ABO group & Rh type

Special handling

Statements

Autologous units

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2
Q

Rapid blood loss

A

Whole blood

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3
Q

Neonatal exchange transfusion

A

Whole blood

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4
Q

Symptomatic anemia

A

Packed RBCs

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5
Q

Avoid febrile or allergic transfusion reactions

A

Deglycerolized RBCs

Washed RBCs

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6
Q

WBC antibodies

A

Leukocyte-poor RBCs

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7
Q

DIC

A

FFP

Platelets

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8
Q

Vitamin K deficiency

A

FFP

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9
Q

Massive transfusions

A

FFP

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10
Q

Thrombocytopenia

A

Platelets

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11
Q

ITP

A

Platelets

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12
Q

Volume expander

A

Plasma

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13
Q

Hemophilia A

A

Cryoprecipitate

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14
Q

Factor XIII deficiency

A

Cryoprecipitate

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15
Q

Hypofibrinogenemia

A

Cryoprecipitate

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16
Q

Neutropenia

A

Granulocytes

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17
Q

Sepsis

A

Granulocytes

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18
Q

Separated from WB by centrifugation or sedimentation any time before expiration date of WB, or collected by apheresis.

A

RBCs

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19
Q

Additive solution added to RBCs following removal of most plasma.

A

RBCs adenine, saline added

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20
Q

Frozen in glycerol within 6 days of collection.

A

RBCs frozen

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21
Q

High glycerol (40%) method most commonly used.

A

RBCs frozen

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22
Q

RBCs washed with saline.

A

Washed RBCs

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23
Q

Filtration or apheresis processing.

A

RBCs leukocytes reduced

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24
Q

Irradiation at 2,500 cGy.

A

RBCs irradiated

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25
Q

Plasma separated from WB & frozen within 8 hr of collection

A

Fresh frozen plasma (FFP)

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26
Q

Prepared by thawing FFP at 1°–6°C, removing plasma, & refreezing within 1 hr

A

Cryoprecipitate

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27
Q

Centrifugation of WB at RT within 8 hrof collection.

A

Platelets

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28
Q

Apheresis.

A

Apheresis platelets

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29
Q

WBCs removed by filtration or during apheresis processing.

A

Leukocytereduced platelets

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30
Q

4–6 ABO-identical plt pooled using closed system.

A

Pre storage pooled platelets

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31
Q

1°–6°C

A

RBCs

RBCs adenine, saline added

Washed RBCs

RBCs leukocytes reduced

RBCs irradiated

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32
Q

Frozen in high glycerol: ≤65°C.

A

RBCs frozen

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33
Q

After deglyc (washing in decreased concentration of saline): 1°6°C

A

RBCs frozen

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34
Q

Frozen: ≤-18°C.

A

Fresh frozen plasma (FFP)

Cryoprecipitate

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35
Q

After thawing: 1°-6°C

A

Fresh frozen plasma (FFP)

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36
Q

After thawing: RT

A

Cryoprecipitate

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37
Q

20°–24°C

A

Platelets

Apheresis platelets

Leukocytereduced platelets

Pre storage pooled platelets

38
Q

35 days in CPDA-1

A

RBCs

39
Q

42 days

A

RBCs adenine, saline added

40
Q

Frozen: 10 yr.

A

RBCs frozen

41
Q

After degylc: 24 hr (unless closed system used)

A

RBCs frozen

42
Q

24 hr after washing

A

Washed RBCs

43
Q

Closed system: same as RBCs.

A

RBCs leukocytes reduced

44
Q

Open system: 24 hr

A

RBCs leukocytes reduced

45
Q

Original outdate or 28 days from irradiation, whichever comes 1st

A

RBCs irradiated

46
Q

Frozen: 12 mo.

A

Fresh frozen plasma (FFP)

Cryoprecipitate

47
Q

After thawing: 24 hr

A

Fresh frozen plasma (FFP)

48
Q

After thawing: single units 6 hr, pools 6 hr if sterile connecting device used, other- wise 4 hr

A

Cryoprecipitate

49
Q

5 days from collection with agitation.

A

Platelets

Apheresis platelets

50
Q

After pooling, 4 hr

A

Platelets

51
Q

Open system—4 hr.

A

Leukocytereduced platelets

52
Q

Apheresis— 5 days

A

Leukocytereduced platelets

53
Q

5 days from collection

A

Pre storage pooled platelets

54
Q

Inadequate tissue oxygenation

A

RBCs

55
Q

Same

A

RBCs adenine, saline added

RBCs frozen

Apheresis platelets

Pre storage pooled platelets

56
Q

History of severe allergic rxn (e.g., IgA, other plasma proteins)

A

Washed RBCs

57
Q

History of febrile rxn

A

RBCs leukocytes reduced

58
Q

Immunodeficiency, malignancy, bone marrow transplant, tf with blood from blood relative, intrauterine & neonatal tf

A

RBCs irradiated

59
Q

Deficiency of coag factors

A

Fresh frozen plasma (FFP)

60
Q

Fibrinogen & factor XIII deficiencies

A

Cryoprecipitate

61
Q

Severe thrombocytopeniaor abnormal platelet function

A

Platelets

62
Q

Recurrent febrile rxn & to decrease risk of CMV transmission or HLA alloimmunization

A

Leukocytereduced platelets

63
Q

Should have HCT ≤80%; otherwise not enough preservative to support RBCs.

A

RBCs

64
Q

1 unit should increase HGB 1 g/dL or HCT 3%.

A

RBCs

65
Q

Most commonly used RBC product.

A

RBCs adenine, saline added

66
Q

Osmolality to monitor glycerol removal.

A

RBCs frozen

67
Q

Virtually all plasma, anticoagulant, WBCs, & platelets removed.

A

RBCs frozen

68
Q

Safe for IgAdeficient pt.

A

RBCs frozen

69
Q

Used to store rare cells.

A

RBCs frozen

70
Q

Not a substitute for leuko- reduced RBCs.

A

Washed RBCs

71
Q

About 20% of RBCs lost in process.

A

Washed RBCs

72
Q

Must retain 70- 85% of original RBCs. <5 × 106 WBCs.

A

RBCs leukocytes reduced

73
Q

For prevention of graft-vs.-host disease.

A

RBCs irradiated

74
Q

Kills donor T cells.

A

RBCs irradiated

75
Q

Contains all coag factors.

A

Fresh frozen plasma (FFP)

76
Q

Check for evidence of thawing & refreezing.

A

Fresh frozen plasma (FFP)

77
Q

Thawed at 30°–37°C or by FDA-approved microwave.

A

Fresh frozen plasma (FFP)

78
Q

Used for hemophilia A & von Willebrand disease only if factor VIII concentrate or recombinant factor preparations not available.

A

Cryoprecipitate

79
Q

Should contain ≥80 IU of factor VIII & ≥150 mg of fibrinogen.

A

Cryoprecipitate

80
Q

40–70 mL plasma.

A

Platelets

81
Q

pH ≥6.2.

A

Platelets

82
Q

1 unit should increase pltby 5,000–10,000/μL in 75-kg recipient.

A

Platelets

83
Q

Shouldn’t be used if visible aggregates present.

A

Platelets

84
Q

May contain residual RBCs.

A

Platelets

85
Q

Usually pooled (4–6 units).

A

Platelets

86
Q

≥5.5 ×1010 plt.

A

Platelets

87
Q

≥3.0 ×1011 plt.

A

Apheresis platelets

88
Q

Equiva-lent to 4–6 units.

A

Apheresis platelets

89
Q

Exposes recipient to fewer donors.

A

Apheresis platelets

90
Q

Extended outdate over-comes need for tfservice to pool just before administration.

A

Pre storage pooled platelets

91
Q

1st soft spin yields platelet-rich plasma. 2nd hard spin separates pltfrom plasma.

A

Platelets

[Immunohematology] Lec (35 decks)

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