4-CHAPTER-II-LESSON-2

Question 1

Represents phenotypes that show weaker variable serologic reactivity with the commonly used human polyclonal anti-A, anti-B, and anti-AB reagents.

Answer 1

ABO SUBGROUPS

Question 2

The weaker (?) is attributed to the decreased number of A and B antigen sites on their red cells.

Answer 2

serologic reactivity of ABO subgroups

Question 3

In 1911, von Dungern descried (?) based on reactions between group A RBCs and anti-A and anti-A1.

Answer 3

two different A antigens

Question 4

Cause discrepancies in ABO testing and cross matches.

Answer 4

A SUBGROUPS

Question 5

Group A RBCs that react with both anti-A and anti-A1 are classified as ?

Answer 5

A1

Question 6

Those that react with anti-A and not anti-A1 are classified as ?.

Answer 6

A2

Question 7

Classification into A1 and A2 cells account for (?) of all group A individuals.

Answer 7

99%

Question 8

BLOOD GROUP A1 ANTI-A REAGENT

Answer 8

+

Question 9

BLOOD GROUP A1 ANTI-A1 LECTIN REAGENT

Answer 9

0

Question 10

BLOOD GROUP A2 ANTI-A REAGENT

Answer 10

+

Question 11

BLOOD GROUP ANTI-A1 LECTIN REAGENT

Answer 11

+

Question 12

Number of antigen sites

Answer 12

QUANTITATIVE

Question 13

Amount of transferase enzyme

Answer 13

QUANTITATIVE

Question 14

Amount of branching

Answer 14

QUANTITATIVE

Question 15

Differences in the precursor oligosaccharide chains

Answer 15

QUALITATIVE

Question 16

Subtle differences in transferase enzymes

Answer 16

QUALITATIVE

Question 17

Formation of anti-A1, in a percentage of some subgroups

Answer 17

QUALITATIVE

Question 18

The immunodominant sugar on both A1 and A2 RBCs is ?

Answer 18

N-actyl- D-galactosamine

Question 19

Differentiation of (?) can be determined by using a reagent made from the seeds of the plant Dolichos biflorus

Answer 19

A1 and A2 phenotypes

Question 20

is found in greatest concentration on the RBCs of O individuals

Answer 20

H antigen

Question 21

Reactivity of anti-H antisera or anti-H lectin with ABO blood groups:

Answer 21

O > A2 > B > A2B > A1 > A1B

Question 22

• agglutinates A1 or A1B

Answer 22

Dolichos biflorus

Question 23

B cells

Answer 23

Bandeiraea simplicifoliaagglutinates

Question 24

• agglutinates O cells (H specificity) and other ABO blood groups depending on the amount of H antigen available

Answer 24

Ulex europaeus

Question 25

In accordance with Landsteiner’s rule for expected ABO antibodies, sera from group O and B individuals contain ?.

Answer 25

anti-A antibodies

Question 26

The anti-A produced by group O and B individuals can be separated by adsorption and elution techniques into two components:

Answer 26

anti-A and anti-A1

Question 27

is specific for the A1 antigen and does not agglutinate A2 red cells.

Answer 27

Anti-A1

Question 28

The optimal reactivity of this antibody is at ?.

Answer 28

room temperature or lower

Question 29

is not considered clinically significant for transfusion purposes.

Answer 29

Anti- A1

Question 30

Anti-A1 becomes a concern when it causes problems with (?) on immediate spin.

Answer 30

ABO phenotyping results and incompatible crossmatches

Question 31

? does not exist because the A2 phenotype possesses the same A antigens as A1 phenotype but in reduced quantities.

Answer 31

Anti-A2

Question 32

Individuals with A1 phenotype do not respond immunologically when exposed to ? .

Answer 32

A2 red cells