Crohns Flashcards
1
Q
Possible etiology
A
Disordered response to intestinal bacteria
2
Q
Location
A
Any portion of the GI,
ususally the terminal ileum, and colon
Skip lesion and rectal sparing
3
Q
Gross morphology
A
Transmural inflam, Cobblestonne mucosa Creeping fat Bowel wall thickening (string sign on barium swallow) Linear ulcers Fissures Fistulas
4
Q
Microscoping
A
Noncaseating granuloma and lymphoid aggregate
TH1 mediated
5
Q
Complication
A
Strictures, Fistulas, Perinanal disease Malabsorption, Nutriotional depletion, Colorectal cancer
6
Q
Intestinal manifestation
A
Diarrhea may or may not be bloody
7
Q
Extraintestinal manifestation
A
Migratory polyarthritis, erythema nodosum ankylosing spondylitis uveitis, kidney stones
8
Q
Treatment
A
Corticosteroid azathioprine MTX infliximab adalimumab
9
Q
How to think of crohns
A
For Crohn’s, think of a fat granny and one crone skipping down a cobblestone road away from the wreck (rectal sparing)
