Metoclopramide Flashcards

1
Q

MOA

A
D2 receptor antagonist
Increased resting tone
contractility
LES tone
Motility

Does not influence colon transport time

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2
Q

Use

A

Diabetic and post-surgery gastroparesis

Antiemetic

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3
Q

Toxicity

A

Increased parkinson effects
Restlessness, drowsiness, fatigue, depression, nausea, diarrhea

Drug interaction with digoxin, diabetic agent.

Contraindicated in pts with small bowel obstruction or Parkinson’s disease.

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