GU Flashcards
What is Leuprolide? What does it do? How do I remember?
GnRH**. Agonist if **pulsatile** => Fertile. Antagonist if **continuous** => fight prostate cancer. **Leude behavior like a pro is disgusting; I lide it gets my genitals going.
What is Methyltestosterone? What are the side effects?
What is Danazol? What is it for? What are the side effects? How do I remember this?
Pre-testosterone => Testosterone. Small balls and premature closure of epiphyseal plates (teratogen).
Partial testosterone agonist. Used to treat Endometriosis** and **Hereditary Angioedema. Masculinization, weight gain, and edema. Danzo is a genocidal guy with partially good intentions to rid those blood eyes (angioedema) and endometriosis.
What are estrogen drugs used for? What are the key risks whenever giving estrogen?
What is a SERM?
How does Clomiphene work? What is it used for? What are the side effects? How do I remember this shit?
How does Raloxifene work? What is it used for? How do I remember this shit?
How do Progestins work for birth control?
Hormone replacement therapy, rarely used birth control, and androgen-dependent prostate cancers. Increased risk of endometrial cancer/clotting.
Selective Estrogen-Receptor modulators.
blocks feedback inhibition => GnRH => LH/FSH => ovulation**. #1 treatment for an/oligoovulation. Multiple simultaneous pregnancies, visual disturbances, ovarian enlargement, and hot flashes. A _Clo_ne of **mi** **phenedishly sexy penis blocks all inhibition in women => super women.
Selective agonis on bone** => **treat osteoporosis**. **Roxanne** is a **fene** to dance(no OP) like that, it talks to my **boner
Thickening of cervical mucus/inhibit endometrial proliferation (less menstruation and prevents implantation)
What is Finasteride? What does it treat?
How do I remember this shit?
What is Flutamide? What is it used in?
What are the secondary testosterone inhibitors? What are they used for? What can they also cause?
5α-reductase inhibitor => inhibits DHT => treat BPH/baldness.
I _Fin_ished growing and my _as_ to ride is huge, I don’t need DHT too.
Competitive inhibitor of testosterone. Prostate cancer
I Flu** **ta** **mide prostate cancer clinic.
Ketoconazole (Inhibits Desmolase) and Spironolactone (Inhibits steroid binding). Polycystic ovarian syndrome. Gynecomastia and Amenorrhea
What is Tamoxifen? What is it primarily used for? How do I remember this shit?
What are the Aromatase inhibitors? What does Aromatase inhibitors inhibit? How do I remember them?
What are the Abortion drugs? What are they? How do I remember this shit?
- *Tam_my took _tox**ic chemo for her ER-positive breast cancer and now takes Tamoxifen** to **fend off new breast cancer.
- *Ana** took a strole and was stopped by her Exe mustang’s Aroma. Making her lose some of her feminist views.
Mifepristone (Anti-Progesterone) and Misoprostol (PGE1). Mi** w_ife’s **prist**_ene _**tone**_d vagina _**Miso** clos_e **to keeping if she aborted.
What are Ritodrine/Terbutaline? When do you use them?
β2 agonists to prevent premature contractions. (It is Rito for fetuses to drine peacefully as we try to keep them away from terbulant lines like “Fuck you bitch”)
What is Tamsulosin?
α1-antagonist used for BPH as it is specific to α1A,D(Prostate) not α1B (vascular). Tam**my _**su** **l**_ucky t**o** not have the **sin** of BPH. Even though it is like **A** she **Don’t have a prostate
What are the basic types of diuretics?
Osmotic diuretics, Carbonic Anhydrase inhibitors, Loop diuretics, Thiazide diuretics, K-sparing diuretics, and ACE inhibitors
What is the osmotic diuretic? What is its MOA? What is it best for?
Mannitol. Forces to piss a lot. Pulmonary edema (especially in anuria)
What is the main Carbonic Anhydrase inhibitor? How does it work? What are the side effects of it?
Acetazolamide. Keeps Bicarbonate from turning into CO2 so it is trapped in the lumen. Alkalizes urine, Acidifies blood**(useful for altitude sickness), neuropathy, **NH3 toxicity, and is sulfa drug
What are the Loop diuretics? What do they inhibit? What do they lose? What are they used for? What are their side effects?
Furosemide(Sulfa) and Ethacrynic acid(not-sulfa). Na/K/2Cl symporter. Ca/K/Na/Cl. Edematous states, HTN, and hypercalcemia. Ototoxicity, Nephritis, and Gout
What is the main Thiazide diuretic? What does it prevent? What does it lose? What is it used for? What are its side effects?
NaCl reabsorption in DCT. Na/K/Cl. calciuria(spares Ca**), HTN, and **nephrogenic diabetes insipidus. Hyperglycemia/Lipidemia/Uricemia/Calcemia and is a Sulfa drug
What are the K-sparing diuretics? What do they block?
Spironolactone (antiandrogen**/I Spy Ron Lactating, O_K_**?), Triamterene, Amiloride, Eplerenone. Aldosterone(Spironolactone does it directly)
What are the ACE inhibitors? What is ACE? What does this cause? What are the side effects?
What are they good for?
How do I remember this shit?
Captopril**, Enala_pril, Lisinopril_. Angiotensin-converting enzyme => blocks Angiotensin II and prevents inactivation of bradykinin (kallikrein activates => cough) => high rennin release(reflex), diuresis, and prevents unfavorable heart remodeling. Cough, Angioedema (blood swelling/similar to hives but deeper), Proteinuria, Taste changes, hypOtension, Pregnancy problems(fetal renal damage), Rash, Increased rennin, Lower angiotensin II(CAPTOPRIL**), hyperkalemia, and significantly decreases GFR
HF, Diabetic nephropathy, HTN, LV dysfunction after MI
ACE fighter pilots love the -pril of flying *Cough* K? But I prefer to inhibit those sensations and stay relaxed without children
What are the Angiotensin II Receptor Blockers (ARBs)? What do they do?
The -sartans. Similar to ACE inhibitors but NO kallikrein = NO cough.
