Endocrine System (KT) Flashcards

1
Q

General characteristics of the endocrine system (3)

A
  1. Chronic regulation of homeostasis
  2. Slow and prolonged responses
  3. Interrelated with the nervous system (hypothalamus and posterior pituitary)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ductless system characteristics (2)

A
  1. Hormones produced by specialized cells

2. Carried in blood stream

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Substance synthesized by a specific organ or tissue and secreted

A

Hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hormone secreted into extracellular spaces

A

Paracrine Signaling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Blood carries hormones to other sites

A

Endocrine signaling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hormones act on target cells that…

A

Have specific receptors for specific hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

4 Categories of Hormones

A
  1. Steroids
  2. Peptides
  3. Amines
  4. Eicosanoids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Hormone that is…

  • Made of cholesterol and is nonpolar
  • Lipid soluble and can cross the cell membrane
  • Transduction –> Regulation of DNA transcription
A

Steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Examples of steroids (4)

A
  1. Estrogens like estradiol
  2. Androgens like testosterone
  3. Aldosterone
  4. Cortisol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hormone that is

  • Derived from amino acids
  • Derived from tyrosine or tryptophan
  • Polar or non polar
A

Amine Hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Example of an amine hormone that is membrane soluble

A

Thyroxine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Example of amine hormone that is not membrane soluble

A

Epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Most important amine hormones are made by… (2)

A
  1. Thyroid

2. Adrenal Medulla

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Hormone that is…

  • Short chains of amino acids
  • Cannot cross cell membrane
  • All pituitary hormones
A

Peptide Hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Hormone that is…

  • Derived from fatty acids
  • Most cross the cell membrane
  • Coordinate functions in extracellular fluid
A

Eicosanoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Example of an eicosanoid

A

Prostaglandins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Characteristics of a Negative Feedback Loop (4)

A
  1. Gland is sensative to a concentration of a substance
  2. Concentration exceeds limits–> prevents gland from secreting hormone
  3. Concentration decreases–> secretion increases
  4. Results in relatively stable concentration of both substance and hormone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

The hypothalamus sends signals to the… (2)

A
  1. Body

2. Pituitary Gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q
  • This is really 2 separate glands, developmental origins are key to function
  • Most important endocrine gland for regulation
A

Pituitary Gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

The 2 lobes of the pituitary gland

A
  1. Posterior

2. Anterior

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Lobe that…

  • Does not make any hormones
  • Mostly hypothalamic axons
A

Posterior Lobe of the Pituitary Gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Lobe that…

  • Has 5 types of endocrine cells
  • Controlled by hypothalamic regulatory hormones
A

Anterior Lobe of the Pituitary Gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

2 types of Regulatory Hormones

A
  1. Releasing hormones

2. Inhibiting Hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Posterior Pituitary Hormone…

-Oxytocin (4)

A
  1. Causes contraction of muscles in the uterine walls
  2. Causes muscles associated with milk ejection to contract
  3. Causes contraction of the prostate gland
  4. Significant in emotional bonding (familial and romantic)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Posterior Pituitary Hormone…

-Anti-diuretic Hormone (ADH) (2)

A
  1. Causes kidney to decrease water excretion

2. Increases blood volume–> rise in blood pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Anterior Pituitary Hormone…

-Melanocyte Stimulating Hormone (MSH) Characteristic (1)

A
  1. Increase melanin secretion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Anterior Pituitary Hormone…

-Follicle Stimulating Hormone (FSH) (3)

A
  1. Testes to produce sperm
  2. Follicular development in ovaries
  3. Stimulate secretion of estrogen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Anterior Pituitary Hormone…

-Luteinizing Hormone (LH) (2)

A
  1. Promotes secretion of sex hormones

2. Release of oocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Anterior Pituitary Hormone…

-Growth Hormone (GH) (4)

A
  1. Increase in size and rate of reproduction of body cells
  2. Targets muscles and bones- mobilizes fat and glucose
  3. Enhances movement of amino acids through membranes
  4. Secreted throughout life, really increase at puberty
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Anterior Pituitary Hormone…

-Thyroid Stimulating Hormone (TSH)

A
  1. Controls secretion of thyroid hormone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Anterior Pituitary Hormone…

-Prolactin (PRL) (2)

A
  1. Targets mammary tissue

2. Milk production and secretion

32
Q

Anterior Pituitary Hormone…

-Adrenocorticotropic Hormone (ACTH)

A

Stimulates the adrenal cortex to produce corticosteroids

33
Q

Structure of the thyroid gland (3)

A
  1. 2 lobes and isthmus (inferior to larynx)
  2. Follicular Cells
  3. Parafollicular Cells
34
Q

Characteristics of Follicular Cells (4)

A
  1. Line follicle cavities
  2. Filled with thyroglobulin colloid
  3. Remove iodine from the blood
  4. Secrete t3 and T4
35
Q

What do parafollicular cells produce?

A

Produce calcitonin

36
Q

Thyroid Hormones (2 types of cells)

A
  1. Follicular Cells (Thyroxine and Triiodothyronine)

2. Parafocllicular Cells (Calcitonin)

37
Q

Effects of Thyroxine, T4 (3)

A
  1. Increase Glycogenolsis
  2. Increase protein synthesis
  3. Increase growth
38
Q

Effects of Triiodothyronine T3 (3)

A
  1. Increase Glycogenolsis
  2. Increase protein synthesis
  3. Increase growth
    * 5 times stronger than T4
39
Q

Effects of Calcitonin (3)

A
  1. Decrease blood calcium and phosphorus
  2. Increase renal excretion
  3. Increase osteoblast activity
40
Q

Where are parathyroid gands located?

A

-Posterior surface of thyroid

41
Q

What does the parathyroid consist of?

A

-Many tightly packed secretory cells

42
Q

Immature parathyroid cells

A

Oxyphil and transitional cells

43
Q

What are chief cells?

A

-Produce parathyroid hormone

44
Q

What does the parathyroid hormone do? (4)

A
  1. Increase blood calcium
  2. Decrease renal calcium and phosphorus excretion
  3. Increase osteoclast activity
  4. Increase calcitriol = intestinal calcium absorption
45
Q

Where is the thymus located?

A

Thoracic cavity, posterior to sternum

46
Q

What does the Thymus produce?

A

Thymosin

47
Q

What does thymosin do?

A
  1. Enhances lymphocyte production and competence

2. Most active in infancy and childhood

48
Q

What are the components of the adrenal cortex? (3)

A
  1. Glomerulosa
  2. Fasciculata
  3. Reticularis
49
Q

In the glomerulosa…

A

Aldosterone –> Na and retention

50
Q

In the fasciculate…

A

Cortisol –> Glycogen formation

51
Q

In the reticularis…

A

Androgens –> Secondary sexual characters

52
Q

The adrenal medulla consists of…

A

Chromaffin cells which are modified postganglionic cells of the SNS (Epinephrine and norepinephrine)

53
Q

3 hormones of the Kidney…

A
  1. Renin
  2. Erythropoietin (EPO)
  3. Calcitriol
54
Q

What does Renin do? (1)

A
  1. Start cascade to increase blood pressure
55
Q

What does Erthropoietin do? (1)

A
  1. Erthrocyte production
56
Q

What does Calcitriol do?

A
  1. Increases absorption of digested calcium
57
Q

What is the hormone of the heart? (1)

A
  1. Atrial Natriuretic Peptide (ANP)
58
Q

What does the Atrial Natriuretic peptide hormone do? (2)

A
  1. Suppresses aldosterone and ADH

2. Decrease blood volume and blood pressure

59
Q

Where is the pancreas located?

A

Posterior to stomach

  • Attached to duodenum by duct
  • Exocrine and endocrine function
60
Q
  • Have endocrine function

- Consist of alpha cells, beta cells, and delta cells

A

Islets of Langerhans

61
Q

What do alpha cells do?

A

Glucagon = Increases blood sugar

62
Q

What do beta cells do?

A

Insulin = Decrease blood sugar

63
Q

What do delta cells do?

A

Somatostatin- inhibits glucagon and insulin secretion

-antagonizes GH

64
Q

What do interstitial cells do?

A

-Secrete andogens

65
Q

What does testosterone do?

A
  • Stimulate nurse cells

- Secondary sex characteristics

66
Q

What do nurse cells do?

A

Secrete inhibin

  • Decrease FSH from anterior pituitary
  • Stimulates spermatogenisus
67
Q

What does estrogen in the follicles do?

A
  • Maturation of the oocyte

- Endometrial development

68
Q

What does inhibin do in the female gonads?

A

-Decrease FSH from anterior pituitary

69
Q

Follicles–>

A

Pre-ovulation

70
Q

Corpus Luteum–>

A

Post-ovulation

71
Q

What does estrogens in the corpus luteum do?

A
  • Maturation of the oocyte

- Endometrial development

72
Q

What does progesterone do?

A

-Prepares body for pregnancy

73
Q

Where are pineacytes located?

A

Epithalamus

74
Q

What does the pineal gland secrete?

A

-Melatonin

75
Q

What does melatonin control?

A

Circadian Rhythms

76
Q

What hormones does the posterior pituitary secrete? (2)

A

Oxytocin and antidiuretic hormone.

77
Q

9What hormones does the anterior pituiatary secrete? (7)

A
  1. Melanocyte stimulating hormone
  2. Follicle stimulating hormone
  3. Luteinizing hormone
  4. Growth hormone
  5. Thyroid stimulating hormone
  6. Prolactin
  7. Adrenocorticotrophic hormone