3️⃣ Cardinal signs of inflammation Flashcards
(5 cards)
1
Q
How does vasodilation cause redness and heat?
A
Increased blood flow and capillary congestion in inflamed tissue.
2
Q
How does increased permeability cause swelling?
A
Fluid and plasma proteins leak into interstitium, forming edema.
3
Q
What mediators produce pain in inflammation?
A
Prostaglandins (especially PGE2) and bradykinin sensitise nerve endings.
4
Q
What leads to loss of function in inflamed tissue?
A
Pain, swelling mechanically impair movement; cell/tissue damage disrupts function.
5
Q
What is the role of lymphatics in resolution?
A
They drain edema fluid, proteins, and cellular debris away from the inflamed site.
