3 - Topical Minoxidil Flashcards Preview

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Flashcards in 3 - Topical Minoxidil Deck (15):
1

Minoxidil is available as a 2% and 5% solution and 5% foam

True

2

Minoxidil increases the duration of the anagen growth phase and gradually enlarges miniaturised hair follicles (vellus hairs) into mature terminal hairs

True

3

Minoxidil is an ATP sensitive potassium channel opener

True

4

Vascular endothelial growth factor (VEGF) is a proposed promoter of hair growth stimulated by the adenosine signalling pathways

True (hence mode of action of minoxidil)

5

Minoxidil stimulates prostaglandins in the dermal papillae

True

6

Minoxidil is indicated for male pattern androgenetic alopecia of the vertex of the scalp

True

7

Minoxidil is most efficacious in the treatment of androgenetic alopecia affecting the crown area for up to 12 months

True

8

Twice daily minoxidil therapy should be continued indefinitely as patients who go on to daily maintenance therapy beginning at 12 months may have decreased hair counts

True

9

The 5% formulation is more superior than the 2% formulation in female pattern androgenetic alopecia

True

10

Minoxidil may cause irritant dermatitis

True

11

Minoxidil may cause allergic contact dermatitis

True

12

Minoxidil may cause hypertrichosis of skin other than the scalp if there is inadvertent application to that site

True

13

There is minimal systemic absorption of topical Minoxidil

True

14

Less inadvertent application and systemic absorption may be expected from the foam vehicle than the solution

True

15

Minoxidil is not recommended in pregnant and nursing women

True