302 Brain imaging in cognitive impairment and cognitive reserve Flashcards
What is the diagnostic criteria for Alzheimer’s disease?
1.Markers for beta amyloid
2.Evidence of degeneration
What is FDG-PET?
It can be used to diagnose Alzheimer’s
A particle like B-amyloid can be radiolabelled and used for diagnosis especially in the early stages of disease
Name some different types of dementia
Frontotemporal dementia
Vascular dementia
Alzheimer’s disease
Lewy body dementia
What is disinhibition?
People don’t know how to behave anymore. They loose insight and empathy. There is a disruption in social behaviour
Caused by damage to the frontal lobe
What is a dopaminergic SPECT scan?
It detects the uptake of dopamine in the brain
What is MEG/EEG?
Magnetoencephalography
It measures the activity of synapses
What is cognitive reserve?
The adaptability of cognitive processing underpinning differential susceptibility to brain againg and disease
What is the brain reserve?
The neurones and synapses we are born with
What is BDNF?
Brain derived neurotrophic factor
It’s the biological explanation for increased cognitive reserve in certain people
