Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Immunology > Haplotypes I > Flashcards

Haplotypes I Flashcards

1
Q

What haplotype is expressed by approximately 70% of patients with rheumatoid arthritis?

A

HLA-DR4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What haplotype is expressed by patients with Ankylosing spondylitis?

A

HLA-B27

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What haplotype is expressed by patients with Dermatitis Herpetiformis?

A

HLA-DR3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What haplotype is expressed by patients with Reiters syndrome?

A

HLA-B27

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What haplotype is expressed by patients with Insulin-dependent diabetes?

A

HLA DR3/ HLA DR4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What haplotype is expressed by patients with Psoriasis vulgaris?

A

HLA-C6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What haplotype is expressed by patients with Goodpasture’s syndrome?

A

HLA-DR2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What haplotype is expressed by patients with SLE?

A

HLA-DR2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What haplotype is expressed by patients with pernicious anemia?

A

HLA-DR5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What conditions are characterized by HLA-B27 haplotypes?

A

Psoriasis, Ankylosing spondylitis, Inflammatory Bowel Disease, Reiters syndrome (acronym: PAIR) (p.194)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What conditions are characterized by HLA-DR3 haplotypes?

A

Dermatitis herpetiformis, Insulin-dependent diabetes, Grave’s Disease (p.194)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What conditions are characterized by HLA-DR4 haplotypes?

A

Insulin dependent diabetes, Rheumatoid arthritis (p.194)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Where are Class I HLA antigens found?

A

On all nucleated cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What gene loci distinguish HLA Class I antigens?

A

HLA-A, HLA-B, HLA-C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the function of HLA Class I antigens?

A

To present foreign antigenic peptides to CD8+ T cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where are class II HLA antigens found?

A

On immunologic effector cells (ex. macrophages, DCs, B cells, activated epithelial cells, etc.)

17
Q

What gene loci distinguish HLA Class II antigens?

A

HLA-DP, HLA-DQ, HLA-DR

18
Q

On what chromosome are genes for the HLAs of MHCs encoded?

A

Chromosome 6.

19
Q

What is the function of HLA Class II antigens?

A

To present foreign antigenic peptides to CD4+ T cells.

Immunology (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions