Autoantibodies and Disease II Flashcards

1
Q

What disorders are associated with p-ANCA (MPO-ANCA)?

A

Microscopic polyangiitis, Churg-Strauss syndrome (p.205)

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2
Q

What autoantibodies are associated with SLE?

A

Antinuclear antibodies (ANA), Anti- dsDNA, anti-smith antibodies (p.205)

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3
Q

What autoantibodies are associated with Drug induced lupus?

A

Antihistone antibodies (p.205)

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4
Q

What autoantibodies are associated with Rheumatoid arthritis?

A

Rheumatoid factor, anti CCP antibodies (p.205)

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5
Q

What autoantibodies are associated with Scleroderma (CREST) syndrome?

A

Anticentromere antibodies (p.205)

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6
Q

What autoantibodies are associated with diffuse scleroderma?

A

Anti-Scl-70 (anti DNA topoisomerase I) antibodies (p.205)

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7
Q

What autoantibodies are associated with Primary Billary Cirrhosis (PBS)?

A

Antimitochondrial antibodies (p.205)

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8
Q

What autoantibodies are associated with Celiac Disease?

A

IgA antiendomysial and IgA anti-tissue transglutaminase antibodies (p.205)

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9
Q

What autoantibodies are associated with Goodpasture’s syndrome?

A

Anti-basement membrane antibodies (p.205)

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10
Q

What autoantibodies are associated with Pemphigus Vulgaris?

A

Anti desmoglein antibodies (p.205)

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11
Q

What autoantibodies are associated with Hashimoto’s thyroiditis?

A

Antimicrosomal and antithyroglobulin antibodies (p.205)

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12
Q

What autoantibodies are associated with Polymyositis?

A

Anti-Jo-1, anti-SRP, anti-Mi-2 antibodies (p.205)

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13
Q

What autoantibodies are associated with Sjogren’s syndrome?

A

Anti SSA (anti Ro) and Anti SSB (anti La) antibodies (p.205)

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14
Q

What autoantibodies are associated with mixed connective tissue disease?

A

Anti U1 RNP (ribonucleoprotein) antibodies (p.205)

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15
Q

What autoantibodies are associated with autoimmune hepatitis?

A

Anti- smooth muscle antibodies (p.205)

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16
Q

What autoantibodies are associated with Type I DM?

A

Anti-glutamate decarboxylase antibodies (p.205)

17
Q

What autoantibodies are associated with Wegner’s Granulomatosis (Granulomotosis with polyangiitis)?

A

c-ANCA (p.205)

18
Q

What autoantibodies are associated with Microscopic polyangiitis?

A

p-ANCA (p.205)

19
Q

What autoantibodies are associated with Churg-Strauss syndrome?

A

p-ANCA (p.205)

20
Q

What autoantibodies are associated with dermatomyositis?

A

Anti-Jo-1, anti-SRP, anti-Mi-2 antibodies (p.205)