Autoantibodies and Disease I Flashcards

1
Q

What disorder is associated with antinuclear antibodies (ANA)?

A

SLE (nonspecific) (p.205)

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2
Q

What disorder is associated with anti-dsDNA, anti-Smith antibodies?

A

SLE (p.205)

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3
Q

What disorder is associated with Antihistone antibodies?

A

Drug induced lupus (p.205)

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4
Q

What disorder is associated with Rheumatoid factor and anti-CCP?

A

Rheumatoid arthritis (p.205)

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5
Q

What disorder is associated with Anticentromere antibodies?

A

Scleroderma (CREST syndrome) (p.205)

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6
Q

What disorder is associated with anti- Scl-70 (anti DNA topoisomerase I) antibodies?

A

Diffuse scleroderma (p.205)

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7
Q

What disorder is associated with Antimitochondrial antibodies?

A

Primary Billiary Cirrhosis (PBS) (p.205)

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8
Q

What disorder is associated with IgA antiendomysial, igA anti-tissue transglutaminae?

A

Celiac disease (p.205)

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9
Q

What disorder is associated with anti-basement membrane antibodies?

A

Goodpasture’s syndrome (p.205)

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10
Q

What disorder is associated with anti-desmoglein antibodies?

A

Pemphigus vulgaris (p.205)

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11
Q

What disorder is associated with antimicrosomal, antithyroglobulin antibodies?

A

Hashimoto’s Thyroiditis (p.205)

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12
Q

What disorders are associated with Anti Jo-1, anti SRP, and anti Mi-2 antibodies?

A

Polymyositis, dermatomyositis (p.205)

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13
Q

What disorder is associated with Anti SSA (anti Ro) antibodies?

A

Sjogren’s syndrome (p.205)

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14
Q

What disorder is associated with Anti SSB (anti La) antibodies?

A

Sjogren’s syndrome (p.205)

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15
Q

What disorder is associated with Anti- U1 RNP (ribonucleoprotein) antibodies?

A

Mixed connective tissue disease (p.205)

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16
Q

What disorder is associated with Anti-smooth muscle antibodies?

A

Autoimmune hepatitis (p.205)

17
Q

What disorder is associated with Anti-glutamate decarboxylase?

A

Type I DM (p.205)

18
Q

What disorder is associated with c-ANCA (PR3-ANCA)?

A

Granulomatosis with polyangiitis (Wegner’s) (p.205)