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Immunology > Immunosuppressant Drugs II > Flashcards

Immunosuppressant Drugs II Flashcards

1
Q

What condition is Filgrastim used to treat?

A

Recovery of bone marrow (p.210)

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2
Q

What condition is Sargramostim used to treat?

A

Recovery of bone marrow (p.210)

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3
Q

What conditions is a-interferon used to treat?

A

Hepatitis B and C, Kaposi’s sarcoma, leukemias, malignant melanoma (p.210)

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4
Q

What condition is b-interferon used to treat?

A

Multiple sclerosis (p.210)

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5
Q

What condition is y-interferon used to treat?

A

Chronic granulomatous disease (p.210)

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6
Q

What condition is Oprelvekin used to treat?

A

Thrombocytopenia (p.210)

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7
Q

What condition is Thrombopoietin used to treat?

A

Thrombocytopenia (p.210)

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8
Q

Name eight therapeutic antibodies.

A

1.) Muromonab-CD3 (OKT3); 2.) Digoxin Immune Fab; 3.) Infliximab; 4.) Adalimumab; 5.) Abciximab; 6.) Trastuzumab (Herceptin); 7.) Rituximab; 8.) Omalizumab (p.210)

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9
Q

What is the therapeutic target of Muromonab-CD3 (OKT3)?

A

CD3 (p.210)

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10
Q

What is the therapeutic target of Digoxin Immune Fab?

A

Digoxin (p.210)

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11
Q

What is the therapeutic target of Infliximab?

A

TNF-a (p.210)

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12
Q

What is the therapeutic target of Adalimumab?

A

TNF-a (p.210)

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13
Q

What is the therapeutic target of Abciximab?

A

Glycoprotein Iib/IIIa (p.210)

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14
Q

What is the therapeutic target of Trastuzumab?

A

HER2 (p.210)

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15
Q

What is the therapeutic target of Rituximab?

A

CD20 (p.210)

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16
Q

What is the therapeutic target of Omalizumab?

A

IgE (p.210)

17
Q

What is the clinical use of Muromonab-CD3 (OKT3)?

A

To prevent acute transplant rejection (p.210)

18
Q

What is the clinical use of Digoxin Immune Fab?

A

Antidote for digoxin intoxication (p.210)

19
Q

What is the clinical use of Infliximab?

A

Crohn’s disease, Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (p.210)

20
Q

What is the clinical use of Adalimumab?

A

Crohn’s disease, Rheumatoid arthritis, psoriatic arthritis (p.210)

21
Q

What is the clinical use of Abciximab?

A

To prevent cardiac ischemia in unstable angina and in patients treated with percutaneous coronary intervention (p.210)

22
Q

What is the clinical use of Trastuzumab?

A

HER2 overexpressing breast cancer (p.210)

23
Q

What is the clinical use of Rituximab?

A

B cell non Hodgkin’s lymphoma (p.210)

24
Q

What is the clinical use of Omalizumab?

A

Additional line of treatment for severe asthma (p.210)

Immunology (28 decks)

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