androgen replacembt therapy and PDE5 inhibitors Flashcards
0
Q
What are the AE of androgen therapy?
A
Erythrocytosis, gels cause risk to children and pets, potential infertility, gynecomastia, hyperlipidemia
1
Q
Treatment for hypogonadism, peri menopause, and transgender is androgen replacement. There are 3 routes. Native-depo (IM)-patch. Which is preferred and why?
A
Patches are preferred. This is because it’s a steady state. Less peaks and troughs so no mood swings and labile labido
2
Q
PDE 5 inhibitors are what?
A
Viagra, cialis, Levitra
3
Q
Why are PDE 5 inhibitors given?
A
Erectile dysfunction, pulmonary arterial hypertension
4
Q
What are the AE of PDE5 inhibitors?
A
Headache, flushing, MI, sudden death
5
Q
The presence of NO excess can amplify this effect from along PDE 5 inhibitors.
A
Severe refractory hypotension
No nitrates
