Blood Products And Transfusion Practice Flashcards
What is anaemia?
Deficiency in primary signalling mechanisms
Bone marrow defect
Deficiency in the building blocks
Red cells defect, excessive destruction or shortened life span
How long is the life span of red blood cells?
35 days
How long do you have between blood being delivered on to the ward and starting a transfusion?
30 mins
How long does it take to transfuse a unit of blood?
4 hrs
What is the most compatible blood transfusion donor?
O
What is the most common donor for fresh frozen plasma?
AB
What are the blood products used and their ABO and rhesus matching?
Red cells = ABO, Rh and kell negative (female)
Platelets = ABO, Rh
Fresh frozen plasma = ABO
Granulocytes = ABO, Rh, HLA
What do you check when checking a pt for a blood transfusion?
Bedside independent checks
Wristband, pt confirmation, component label, component, transfusion prescription
Sign and document
What are the acute immune mediated adverse effects of a blood transfusion?
Acute haemolysis Anaphylaxis Transfusion associated lung injury Febrile non-haemolytic Urticaria
What are the acute non immune mediated adverse effects to a blood transfusion?
Bacterial contamination
Circulatory overload
Citrate toxicity
What are the delayed immune mediated adverse effects of a blood transfusion?
Delayed haemolysis
Transfusion associated GVHD
Post transfusion purpura
What are the delayed non immune mediated adverse effects of a blood transfusion?
Iron overload
Disease transmission
What is the normal platelet count?
125-400 x 10 to the power 9
When would irradiated blood products be used?
Hodgkin’s lymphoma
Some cytotoxic chemotherapy
Some treatments that impair the immune system
Stem cell transplant setting
When would CMV negative blood products be used?
Pregnant women
Fetal and neonate transfusions
