Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Virology Exam 2 > Pox Viruses > Flashcards

Pox Viruses Flashcards

1
Q

Entomopoxvirinae

A

pox viruses of insects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Chordopoxvirinae

A

Pox viruses of vertebrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Basic structure of pox viruses

A

Large, sometimes enveloped DNA viruses with complex structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Two distinct infectious particles

A

Intracellular mature virus (IMV)

Extracelluar enveloped virions (EEV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Intracellular mature virions

A

only have an inner membrane. Released by lysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Extracellular enveloped virions

A

have an envelope and inner membrane

released by budding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Genome of Pox virus

A

single molecule of linear double-stranded DNA

encodes proteins that counteract host adaptive and innate immune responses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Replication occurs

A

in the cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pox virus antigenic characteristics

A

Specific nucleoprotein, exposed following alkaline digestion of virus
production of hemaggulation only by Orthopoxviruses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Envelope properties

A

High environmental stablility, long infectious period.

less sensitive to organic solvents/disinfectants due to low lipid content

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Methods of transmission

A

Damaged skin
Respiratory route
Mechanically by biting arthropods
spread by lymphatics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Most pox are host specific except ____

A

Orthopoxviruses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Orthopoxviruses: hosts

A

Cowpox
wide host range
Rodents are reservior

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Cowpox: cattle transmission

A

cow to cow by milker’s hands or teat cups
infected farm cats
rodents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cowpox: cattle Clinical findings

A

papules on teats and udder, suckling calves may have them on mouth
May rupture into ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Cowpox: Cats Transmission

A

skin inoculation by bite or would

oro-nasal route

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Cowpox: Cats Clinical signs

A

single primary skin lesions, followed by widespread secondary lesions as ulcerated papules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Cowpox: Humans Transmission

A

contact with cats most common

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Cowpox: humans Clinical signs

A

papular lesions on hands and face, may ulcerate
enlarged, painful lymph nodes
fever, vomiting, sore throat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Monkeypox: Monkeys

A

generalized skin lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Monkeypox: human transmission

A

direct contact with infected animal fluid (monkey, gambian rat, or squirrel)
contact with infected respiratory excretions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Monkeypox: human clinical signs

A

Invasive period- fever, headache, lymphadenopathy, muscle pain
Skin eruption period- rash of macropapules and vesicles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Parapoxviruses

A

Pseudocowpox

contageious Ecthyma/Orf virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Pseudocowpox condition

A

viral skin disease, causes mild sores on teats and udder of cows
Milker’s nodule- human infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Pseudocowpox transmission

A

contaminated milkers
biting insects
calves get infected by suckling
semen of bulls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Pseudocowpox pathogenesis and CS

A

lesions of hyperplasia of squamous epithelim
high morbidity of mild infection
up to 10 lesions on 1 teat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Pseudocowpox acute lesions

A

thick, elevated scab, falls off, leaving Horse-shoe shaped ring of small wart-like granuloma

28
Q

Pseudocowpox: chronic lesions

A

erythema, yellow/grey scabs that rub off at milking

corrugated skin, no pain

29
Q

Pseudocowpox: Treatment and prevention

A

removal and burning of scabs, apply emollient ointment before milking, astringent prep afterwards
disinfection, teat dip, reduce teat trauma, isolate infected

30
Q

Pseudocowpox: humans

A

Milker’s nodule

lesions on hands

31
Q

Contagious Ecthyma: Hosts

A

Orf virus

Sheep and goats

32
Q

Contagious Ecthyma: transmission

A

scabs from lesions, long infectious period

primary infection by damaged skin.

33
Q

Contagious Ecthyma: Pathogenesis

A

cellular necrosis and sloughing of epidermis
lesion forms scab
immunity last ~8 months

34
Q

Contagious Ecthyma: Clinical signs

A

first lesions develop at lip corners followed by lip swelling
continues to muzzle and nostrils
anorexia and weightloss
lesions also seen on udder, feet, and scrotumm

35
Q

Contagious Ecthyma: Vaccination

A

developed from suspension of scabs.
should not be used on farms that do not have a problem
1-2 years of immunity

36
Q

Contagious Ecthyma: vaccinate lambs at ____ and pregnant ewes ____ before lambing

A

lambs: 6-8 weeks
Ewes: 7-8 weeks before lambing

37
Q

Contagious Ecthyma: Human infections

A

from handling infected animals
large nodular lesions on fingers, hands, arms, face, and penis (wash your hands, boys)
lasts about 4-9 weeks

38
Q

Capripoxvirus

A

Sheep pox
goat pox
Lump skin disease (cattle)

39
Q

Sheeppox and goatpox: Transmission

A

Highly contagious, long infectious period
by respiratory tract
damaged skin by contaminated materials
mechanical by biting arthropods

40
Q

Sheeppox: Pathogenesis

A

systemic disease
leukocyte-asso. viremia
immune complexes = severe necrotizing vaculitis (Type III hypersen.) = ischemic necrosis of dermis

41
Q

Sheeppox: 2 forms of disease

A

Malignant form

Benign form

42
Q

Sheeppox: Malignant form

A

depression, prostration, high fever, salivation, lactrimation, edema of eyelids, mucopurulent nasal discharge.
lesions develop, spread into visera.
scar into star shaped w/o hair or wool
Mortality -50%, up to 100% in lambs

43
Q

Sheeppox: benign form

A

more common in adults

only skin lesions develop or mild systemic reaction

44
Q

Sheeppox: Prevention

A

Reportable- prohibited importation from infected areas

vaccines provide temp. protection

45
Q

Goatpox

A

Reportable, similar to sheeppox
kids suffer systemic disease on skin and viscera
Flat hemorrhagic form had high mortality case

46
Q

Lumpy Skin Disease: transmission

A

most common by arthropods

also direct contact

47
Q

Lumpy Skin Disease: Clinical signs

A

in all cattle ages and breeds

fever, multiple nodular lesions on skin and musoca. lymphadenopathy

48
Q

Lumpy Skin Disease: Control

A

Vaccine

cull infected animals

49
Q

Suipoxvirus

A

Swinepox

50
Q

Swinepox

A

pigs (duh)
typically low mortality and morbidity
high mortality in young pigs

51
Q

Swinepox: transmission

A

direct contact with skin injury, long infectious period
Mechanical via Haematopinus suis.
Transplacental infection

52
Q

Swinepox: Clinical signs

A

transient fever, pox lesions
Exudative epidermitis (Greasy Pig Disease) as a 2nd disease
congenital pox lesions in vicera

53
Q

Swinepox: Control

A

Pest control

no vaccine

54
Q

Avipoxvirus

A

Fowlpox

55
Q

Fowlpox: hosts

A

highly infectious disease of poultry and turkeys

56
Q

Fowlpox: Transmission

A

long infectious period
direct contact to wounds
Mechanically
possibly aerosol route

57
Q

Fowlpox: 3 forms

A 
Cutaneous form (dry form)
Diphtheritic form (wet form)
Ocular form
58
Q

Fowlpox: Cutaneous form characteristics

A

Most common form, low mortalility
small papules on comb, wattles, and around beak (sometimes on legs and cloaca)
Drop in egg prod. Recovery in about 4 weeks

59
Q

Fowlpox: Diphtheritic form characteristics

A

by droplet infection
infection of muous membranes of mouth, pharynx, larynx, and trachea
necrotic pseudomembrane lesions, death by asphyxiation

60
Q

Fowlpox: Ocular form

A

Conjunctivitis

cheesy exudate accumulates under eyelids

61
Q

Avipoxvirus: inclusion bodies

A

Bollinger bodies- eosinophilic granular intracytoplasmatic

Borrel bodies- minute spherical bodies obtained by digestion of Bollinger bodies

62
Q

Fowlpox: control

A

Vaccine

control mosquito population

63
Q

Ulcerative Dermatosis of Sheep

A

unclassified poxvirus

Infectious disease of sheep

64
Q

Ulcerative Dermatosis of Sheep: features

A

transmitted by wound infections or by coitis
Lip and Leg ulceration
Veneral form, ulceration of gentials

65
Q

Diagnosis of Pox virus

A 
clinical signs
Sampling material
Electron microscopy
Histopathology
inoculation of embryonated egg (pox lesions on CAM)
serology and PCR

Virology Exam 2 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions