Papillomaviridae

Question 1

Papillomaviridae characteristics

Answer 1

Non-enveloped, spherical

single, circular double-stranded DNA

Question 2

Papillomaviridae (HPV) forms warts that are ___

Answer 2

Benign hyperplastic epithelial outgrowths

Question 3

T or F

the warts may become malignant

Answer 3

True

Example: cervical carcinoma in women

Question 4

Replication is linked mainly to ____ epithelium

Answer 4

stratified squamous

Question 5

Wart growth is caused by blocking ___

Answer 5

p53

Question 6

Warts are most commonly seen in what species

Answer 6

Bovine

Question 7

HPV: transmission

Answer 7

contaminated fomites

veneral

Question 8

Fibropapilloma is caused by types

Answer 8

Bovine HPV types 1, 2, and 5

Question 9

T or F

Fibropapillomas can be found on the prepuce of bulls

Answer 9

False

Warts are found on the penis

Question 10

Cutaneous papillomas are caused by type

Answer 10

3

Question 11

Cutaneous papillomas are flat and lack a ____ core

Answer 11

Fibrous core

Question 12

Bovine HPV-4 causes warts in GIT, this is aggravated by ingestion of

Answer 12

Bracken fern

results in invasive carcinoma

Question 13

HPV: diagnosis

Answer 13

visible lesions, viruses in TEM

PCR, DNA hybridization

Question 14

HPV: treatment

Answer 14

surgical removal, topical agents, bovine INF-Alpha

Question 15

Canine ____ papillomatosis

Answer 15

Canine Oral papillomatosis

Question 16

COP is characterized by epithelial hyperplasia and cytoplasmic vacuoles called

Answer 16

Koilocytosis

Question 17

COP: clinical signs

Answer 17

Hallitosis (bad breath), hemorrhage, hypersalivation
difficulty eating and drinking
ocular wart

Question 18

COP: treatment

Answer 18

surgical removal

autogenous vaccine, vaccine made from removed wart

Question 19

Feline papillomatosis is typically found in ___

Answer 19

the ear

Question 20

equine papillomavirus is called

Answer 20

Equine sarcoids

Question 21

Most susceptible breeds to sarcoids

Answer 21

Arabians, Appaloosa, american quarter horse

Question 22

Less susceptible breeds

Answer 22

Standardbred and Thoroughbreds

Question 23

Sarcoids: clinical signs

Answer 23

common in traumatic areas, single or multiple
large, may ulcerate
appears as “Proud flesh”

Question 24

Sarcoids: diagnosis

Answer 24

clinical features
histology
viral detection

Question 25

Sarcoids: treatment

Answer 25

surgical removal
local immune modulation
local radiotherapy