Asfarviridae

Question 1

Asfarviridae properties

Answer 1

Enveloped, icosahedral capsid. single, linear, double-stranded DNA

Question 2

Asfarviridae replication in __

Answer 2

the cytoplasm, but nucleus is involved in early stages

Question 3

Asfarviridae causes ___

Answer 3

African swine fever

only member of family, effects all types of swine

Question 4

ASF does not hemagglutinate, it uses a specific protein that a adheres RBCs to monocytes

Answer 4

Hemadsorption

Question 5

Hemadsorption of RBCs is called ____ formation

Answer 5

Rosette formation

Question 6

ASF: transmission

Answer 6

Vector- Ornithodorus (O.moubata) ticks
- trans-stadial, transovarial, sexually in ticks
Direct contact, aserosol

Question 7

ASF: Pathogenesis

Answer 7

hemorrhages, apoptosis

leukopenia, lymphopenia, thrombocytopenia

Question 8

Sites of ASF replication (organs and/or cell types)

Answer 8

Pharyngeal mucosa, tonsils

endothelial cells, megakaryocytes, macrophages

Question 9

ASF: peracute clinical signs

Answer 9

Sudden death

1-3 days of fever, hyperpnea, hyperemia

Question 10

ASF: acute Clinical signs

Answer 10

high fever, anorexia, erythemia, cyantoic skin, vomiting, bloody diarrhea, abortion, death

Question 11

ASF: chronic clinical signs

Answer 11

emaciation and stunted, swollen joints, ulcers and reddened necrotic skin foci, pneumonia

Question 12

ASF: diagnosis

Answer 12

virus isolation, hemadsorption, serology, PCR

Question 13

ASF: Immunity

Answer 13

No vaccine

recovered animals become carriers

Question 14

ASF: control

Answer 14

Reportable

Biosecurity measures, hygiene, no swine parts in feed, monitor animal traffic