3SQ1 Flashcards by LEVI B

Carbon tetrachloride

a. Halogenated Aliphatic Hydrocarbons
b. Aromatic Hydrocarbons

a. Halogenated Aliphatic Hydrocarbons

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Xylene

a. Halogenated Aliphatic Hydrocarbons
b. Aromatic Hydrocarbons

b. Aromatic Hydrocarbons

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This is a tridentate iron chelator is used to treat iron overload caused by blood transfusion

a. Dimercaprol
b. Deferoxamine
c. Deferasirox
d. Deferiprone

c. Deferasirox

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Clinically used as chelator of choice for iron poisoning

a. Dimercaprol
b. Deferoxamine
c. Deferasirox
d. Deferiprone

b. Deferoxamine

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Isolan

a. Organochlorine pesticide
b. Organophosphorus pesticide
c. Carbamate pesticide
d. Botanical pesticides

c. Carbamate pesticide

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Diazinon

a. Organochlorine pesticide
b. Organophosphorus pesticide
c. Carbamate pesticide
d. Botanical pesticides

b. Organophosphorus pesticide

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Pyramat

a. Organochlorine pesticide
b. Organophosphorus pesticide
c. Carbamate pesticide
d. Botanical pesticides

c. Carbamate pesticide

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These herbicides generate N-nitrosodimethylamine
(NDMA) which is a potent human carcinogen:

a. Chlorophenoxy
b. Glyphosate
c. Bipyridyl

a. Chlorophenoxy

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This is a brownish irritant gas associated with fires and causes silo-filler’s disease:

a. Carbon monoxide
b. Sulfur dioxide
c. Nitrogen oxide
d. Ozone

c. Nitrogen oxide

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“This is a colorless, tasteless, odorless and nonirritating gas byproduct of incomplete combustion”

a. Carbon monoxide
b. Sulfur dioxide
c. Nitrogen oxide
d. Ozone

a. Carbon monoxide

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This combines tightly but reversibly with oxygen binding sites of hemoglobin

a. Carbon monoxide
b. Sulfur dioxide
c. Nitrogen oxide
d. Ozone

a. Carbon monoxide

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Environmental pollutant used in coolant materials of
air-conditioning systems:

a. Polychlorinated biphenyls (PCBs)
b. Asbestos
c. Perfluorinated Compounds (PFCs)
d. Endocrine Disruptors

c. Perfluorinated Compounds (PFCs)

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Exposure to this may come from batteries, electroplating or galvanizing:”

a. Arsenic
b. Beryllium
c. Cadmium
d. Mercury

c. Cadmium

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The organic form of this heavy metal may cause encephalopathy:

a. Arsenic
b. Beryllium
c. Cadmium
d. Lead
e. Mercury

d. Lead

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This confers special properties to alloys and metals

a. Arsenic
b. Beryllium
c. Cadmium
d. Lead
e. Mercury

b. Beryllium

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This interferes with heme synthesis:

a. Arsenic
b. Beryllium
c. Cadmium
d. Lead
e. Mercury

d. Lead

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Clinically used for treatment of radioactive cesium contamination

a. Succimer
b. Unithiol
c. Penicillamine
d. Prussian Blue

d. Prussian Blue

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Major effect of organochlorine pesticides

a. Respiratory depression
b. Cholinergic stimulation
c. Hyperreactive airways
d. CNS stimulation

d. CNS stimulation

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Damages the lung infrastructure that produces the surfactant

a. CO
b. Ozone
c. Hydrogen sulfide
d. NO

d. NO

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True of carbamate poisoning compared to
organophosphates EXCEPT

a. Less risk of poisoning because of larger therapeutic index
b. Spontaneous reactivation of cholinesterase is more rapid
c. Pralidoxime is indicated for both to reverse its effects
d. Clinical effects are of shorter duration

c. Pralidoxime is indicated for both to reverse its effects

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Concerned with the toxic effects of chemical and physical agents on populations and communities of living
organisms within defined ecosystems

a. Occupational toxicology
b. Environmental toxicology
c. Ecotoxicology
d. Industrial toxicology

c. Ecotoxicology

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Least affected by halohydrocarbons

a. Liver
b. Kidneys
c. Heart
d. Lungs

d. Lungs

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Second-line oral chelator for patients with transfusional iron overload due to thalassemia

a. Deferiprone
b. Deferoxamine
c. Penicillamine
d. Deferasirox

a. Deferiprone

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Interacts with sulfhydryl groups, inhibiting enzymes and altering cell membranes

a. Lead
b. Arsenic
c. Mercury
d. More than 2 choices are correct

d. More than 2 choices are correct

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Interference with the action of essential cations, (Ca+2, Fe+2, & Zn+2) a. Lead b. Arsenic c. Mercury d. More than 2 choices are correct

a. Lead

Environmental pollutant used as heat transfer fluid, lubricating oil and flame retardants: a. Perfluorinated Compounds (PFCs) b. Polychlorinated biphenyls (PCBs) c. Asbestos d. Endocrine Disruptors

b. Polychlorinated biphenyls (PCBs)

Environmental pollutant used in coolant materials of air conditioning systems: a. Perfluorinated Compounds (PFCs) b. Polychlorinated biphenyls (PCBs) c. Asbestos d. Endocrine Disruptors

a. Perfluorinated Compounds (PFCs)

Genetically modified crops were developed to have resistance to this type of herbicide: a. Chlorphenoxy b. Glyphosate c. Bipyridy

b. Glyphosate

These herbicides generate N-nitrosodimethylamine (NMDA) which is a potent human carcinogen a. Chlorphenoxy b. Glyphosate c. Bipyridyl

a. Chlorphenoxy

Clinically used for treatment of radioactive cesium contamination a. Succimer b. Unithiol c. Penicillamine d. Prussian Blue

d. Prussian Blue

This is a bidentate iron chelator is used as a second line chelator for patients with transfusional overload due to thalassemia a. Dimercaprol b. Deferoxamine c. Deferasirox d. Deferiprone

d. Deferiprone

This is a tridentate iron chelator is used to treat iron overload caused by blood transfusion a. Dimercaprol b. Deferoxamine c. Deferasirox d. Deferiprone

c. Deferasirox

Clinically used for copper poisoning like in Wilson's disease a. Edetate Calcium Disodium b. Deferoxamine c. Penicillamine d. Succimer e. Dimercaprol

c. Penicillamine

This is metabolized by methylation and eliminated majority thru the kidneys a. Arsenic b. Beryllium c. Cadmium d. Lead

a. Arsenic

This confers special properties to alloys and metals a. Arsenic b. Beryllium c. Cadmium d. Lead e. Mercury

b. Beryllium

"Exposure to this may come from batteries, gasoline and paints:" a. Arsenic b. Beryllium c. Cadmium d. Lead e. Mercury

d. Lead

“Exposure to this may come from batteries, electropainting or galvanizing:" a. Arsenic b. Beryllium c. Cadmium d. Lead e. Mercury

c. Cadmium

"This is can be eliminated majority thru the kidneys, feces, sweat and breastmilk a. Arsenic b. Beryllium c. Cadmium d. Lead e. Mercury

d. Lead

Parathion a. Organochlorine pesticide b. Organophosphorus pesticide c. Carbamate pesticide d. Botanical pesticides

b. Organophosphorus pesticide

Trichlorfon a. Organochlorine pesticide b. Organophosphorus pesticide c. Carbamate pesticide d. Botanical pesticides

b. Organophosphorus pesticide

Least concern of preventive systems in the workplace a. Oral b. Transdermal c. Inhalational d. Injection

a. Oral

Chronic exposure a. Intense, rapid absorption b. Detoxifying systems overwhelmed c. Accidental discharge of chemicals d. Repetitive handling of a chemicals

d. Repetitive handling of a chemicals

Long-term effect of organophosphate poisoning secondary to its action on NTE enzyme a. OPIDP b. Progressive chronic axonal neurotoxicity c. Cardiac failure d. Progressive weakness of respiratory muscles

a. OPIDP

True of carbamate poisoning compared to organophosphates EXCEPT a. Less risk of poisoning because of larger therapeutic index b. Spontaneous reactivation of cholinesterase is more rapid c. Pralidoxime is indicated for both to reverse its effects d. Clinical effects are of shorter duration

c. Pralidoxime is indicated for both to reverse its effects

Primary route of entry of chemicals in industrial setting a. Oral b. Transdermal c. Inhalational d. Injection

c. Inhalational

A colorless irritant gas generated from combustion of fossil fuels a. Carbon monoxide b. Sulfur dioxide c. Nitrogen oxide d. Ozone

b. Sulfur dioxide

This has severe irritant effects on the eyes and mucous membranes. a. Carbon monoxide b. Sulfur dioxide c. Nitrogen oxide d. Ozone

b. Sulfur dioxide

This is a brownish irritant gas associated with fires and causes sil-filler's disease: a. Carbon monoxide b. Sulfur dioxide c. Nitrogen oxide d. Ozone

c. Nitrogen oxide

Perchloroethylene a. Halogenated Aliphatic Hydrocarbons b. Aromatic Hydrocarbons

a. Halogenated Aliphatic Hydrocarbons

Chloroform a. Halogenated Aliphatic Hydrocarbons b. Aromatic Hydrocarbons

a. Halogenated Aliphatic Hydrocarbons

Parenteral chelator of choice for Iron poisoning OR Clinically used chelator of choice for iron poisoning a. Prussian blue b. Deferoxamine c. Penicillamine d. Deferasirox

b. Deferoxamine

Seizures a. Arsenic b. Lead c. Mercury d. More than 2 choices are correct

b. Lead

Deleterious effect of chemical pollutants to the environmental and living organisms a. permissible exposure limit b. Hazard c. risk d. ecotoxicology

d. ecotoxicology

Allowable limits to chemical substance before symptoms of toxicity occurs a. permissible exposure limit b. Hazard c. risk d. ecotoxicology

a. permissible exposure limit

<24 hours of exposure a. acute b. subacute c. subchronic d. chronic

b. subacute

1 month of repeated exposure a. acute b. subacute c. subchronic d. chronic

c. subchronic

1-3 mos of repeated exposure a. acute b. subacute c. subchronic d. chronic

d. chronic

dose delivered at a single event a. acute b. subacute c. subchronic d. chronic e. None of the above

e. None of the above

colorless; tasteless; seen in generators a. carbon monoxide b. sulfur dioxide c. nitrogen oxide d. ozone e. all of the above

a. carbon monoxide

bluish, irritating gas found in burning fossil fuel a. carbon monoxide b. sulfur dioxide c. nitrogen oxide d. ozone e. all of the above

d. ozone

delayed onset pulmonary edema a. carbon monoxide b. sulfur dioxide c. nitrogen oxide d. ozone e. all of the above

b. sulfur dioxide

brownish irritant gas a. carbon monoxide b. sulfur dioxide c. nitrogen oxide d. ozone e. all of the above

c. nitrogen oxide

farmers are most susceptible to this gas due to the farm fires a. carbon monoxide b. sulfur dioxide c. nitrogen oxide d. ozone e. all of the above

c. nitrogen oxide

combining of the gas to hemoglobin a. carbon monoxide b. sulfur dioxide c. nitrogen oxide d. ozone e. all of the above

a. carbon monoxide

HH, 40/M, farmer sought consult because of multiple hyperkeratotic skin bumps on his hands and feet. You are suspecting an exposure to a chemical. You are thinking of arsenic poisoning. Classify the ff: gastrointestinal symptoms a. acute intoxication b. chronic intoxication

a. acute intoxication

HH, 40/M, farmer sought consult because of multiple hyperkeratotic skin bumps on his hands and feet. You are suspecting an exposure to a chemical. You are thinking of arsenic poisoning. Classify the ff: respiratory symptoms a. acute intoxication b. chronic intoxication

a. acute intoxication

HH, 40/M, farmer sought consult because of multiple hyperkeratotic skin bumps on his hands and feet. You are suspecting an exposure to a chemical. You are thinking of arsenic poisoning. Classify the ff: hair and nail manifestation a. acute intoxication b. chronic intoxication

b. chronic intoxication

as single agent in acute arsenic and inorganic mercury poisoning a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

c. Dimercaprol

parenteral chelator of choice for iron intoxication a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

e. Deferoxamine

water soluble chelator of lead a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

a. succimer, dimercaptosuccinic acid (DMSA)

used to treat children with blood lead level concentration >45mcg/dl a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

a. succimer, dimercaptosuccinic acid (DMSA)

water soluble analog of dimercaprol for arsenic and mercury intoxication a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

d. Unithiol

prevents the reverse metal-induced inhibition of sulfhydryl containing enzymes a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

a. succimer, dimercaptosuccinic acid (DMSA)

antidote used to a warfare agent called lewesite a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

c. Dimercaprol

problem and disadvantage of this agent for acute arsenic poisoning is it redistributes the metal a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

c. Dimercaprol

a chelator that protective against mercury and arsenic poisoning however has no FDA approval for any indication a. succimer, dimercaptosuccinic acid (DMSA) b. Edetate calcium disodium c. Dimercaprol d. Unithiol e. Deferoxamine

d. Unithiol

activated charcoal would not be effective for the ff, EXCEPT: a. alcohol b. barbiturate c. cyanide d. iron

b. barbiturate

which of the following do not enhance the elimination of poisons? a. activated charcoal b. urinary retention c. urine acidification d. dialysis

b. urinary retention

alkalinization therapy would be effective for excretion of: a. amphetamines b. barbiturates c. theophylline d. phenytoin

a. amphetamines

which antidote is a competitive inhibitor at receptor site? a. atropine b. ethanol c. chelating agent d. digoxin-fab

a. atropine

which neutralizing agent is used for caustic agents? a. egg white albumin b. starch c. sodium bicarbonate d. potassium permanganate

d. potassium permanganate

antidote for cyanide poisoning: a. esmolol b. ethanol c. fomepizole d. hydroxocobalamin

b. ethanol

dimercaprol/BAL is contraindicated in the following, EXCEPT: a. arsenic b. cadmium c. copper d. methylmercury

c. copper

used to establish safe ambient air concentrations for many chemicals found in the workplace a. ADI b. OSHA c. PEL d. TLV

b. OSHA

concerned with the toxic effects of chemical and physical agents on populations and communities of living organisms within defined ecosystems a. ecotoxicology b. environmental toxicology c. occupational toxicology d. industrial toxicology

a. ecotoxicology

genetically modified crops were developed to have resistance to this type of herbicide: a. bipyridyl b. chlorphenoxy c. glycophosate

c. glycophosate

exposure to this may come form batteries, gasoline and paints: a. beryllium b. cadmium c. lead d. mercury

c. lead

damages the lung infrastructure that produces the surfactant a. CO b. Hydrogen sulfide c. ozone d. NO

d. NO

major concern with chronic exposure to benzene a. aplastic anemia b. CNS depression c. GI bleeding d. Respiratory irritation

a. aplastic anemia

primary route of entry of chemicals in the industrial setting a. oral b. inhalational c. transdermal d. injection

b. inhalational

inhalation of this may cause progressive pulmonary fibrosis a. beryllium b. cadmium c. both d. neither

c. both

result of overzealous treatment of CO poisoning: a. ARDS b. asthma c. perfluorinated compounds d. polychlorinated biphenyls

c. perfluorinated compounds

FDA approved oral treatment of iron overload caused by blood transfusions a. deferiprone b. penicillamine c. deferoxamine d. deferasirox

d. deferasirox

this dimercapto chelating agent exhibits protective effects against the action of mercury and arsenic has reported allergic reactions including Steven-Johnson syndrome a. succimer b. penicillamine c. prussian blue d. unithiol

d. unithiol

parenteral chelator of choice for iron poisoning: a. prussian blue b. penicillamine c. deferoxamine d. deferasirox

c. deferoxamine

methyl chloroform a. aromatic hydrocarbons b. halogenated aliphatic hydrocarbons

b. halogenated aliphatic hydrocarbons

toluene a. aromatic hydrocarbons b. halogenated aliphatic hydrocarbons

a. aromatic hydrocarbons

carbofuran a. botanical pesticides b. carbamate pesticide c. organochlorine pesticide d. organophosphorus pesticide

b. carbamate pesticidec

dieldrin a. botanical pesticides b. carbamate pesticide c. organochlorine pesticide d. organophosphorus pesticide

c. organochlorine pesticide

malathion a. botanical pesticides b. carbamate pesticide c. organochlorine pesticide d. organophosphorus pesticide

d. organophosphorus pesticide

torsades de pointes a. arsenic b. lead c. mercury d. all of the given

a. arsenic

seizures a. arsenic b. lead c. mercury d. all of the given

b. lead

clinically used for chelation of lead as well as zinc and manganese a. dimercaprol b. edetate calcium disodium c. succimer d. penicillamine

b. edetate calcium disodium

clinically used for copper poisoning like in Wilson's disease a. dimercaprol b. edetate calcium disodium c. succimer d. penicillamine

d. penicillamine

3SQ1 Flashcards

(104 cards)