Lec 14 Pyruvate Metabolism

Question 1

pyruvatate that goes through anaerobic metabolism produces blank which cause blank

Answer 1

lactate, cavities

Question 2

important enzyme for digesting galactose

Answer 2

galactose 1 phosphate (uridylyl transferase)

Question 3

blank is required for making glycogen, digesting galactose, and making sphingolipid

Answer 3

udp glucose

Question 4

when galactose can not be metabolized

Answer 4

galactosemia

Question 5

galactosemia has unmetabolized milk sugars called blank which build up and damage the liver, eyes, kidneys, and brain…..

Answer 5

galactitol

Question 6

important things used by brain in the fasted state

Answer 6

ketone bodies

Question 7

center of the entire metabolic scheme

Answer 7

pyruvate

Question 8

almost anything can be made from blank

Answer 8

pyruvate

Question 9

enzyme that regenerates nad+ in the human body

Answer 9

lactate dehydrogenase

Question 10

hangover is due to this molecule in alcohol digestion

Answer 10

acetaldehyde

Question 11

three subunits of pyruvate dehydrogenase complex

Answer 11

E1, E2, E3

Question 12

E1 reaction is blank

Answer 12

irreversible

Question 13

E2 and E3 are both blank

Answer 13

reversible

Question 14

regulation targets blank reaction because of its irreversibility

Answer 14

E1

Question 15

what is produced by e2

Answer 15

acetyl coA

Question 16

what is made by e1 reaction

Answer 16

co2

Question 17

what is made by e3

Answer 17

nadh

Question 18

pdc is inhibited by blank which makes ground water toxic

Answer 18

asinine

Question 19

fast twitch fibers convert pyruvate to blank

Answer 19

lactate

Question 20

slow twtich fibers convert pyruvate to blank which is converted to blank

Answer 20

acetyl coA, co2 + h2o

Question 21

cycle that takes glucose from blood and converts it to lactate then the liver uses the lactate and turns it back into pyruvate then glucose

Answer 21

cori cycle

Question 22

normal amount of blood lactate

Answer 22

1 mM

Question 23

hyperlactemia is this range of blood lactate concentration

Answer 23

2-5 mM

Question 24

> 5 mM blood lactate concentration is blank

Answer 24

lactic acidosis

Question 25

glucose is converted to blank

Answer 25

2 pyruvate