Trimetaphan (Arfonad) Flashcards
1
Q
Description
A
Nicotinic ganglionic blocker (non-depolarizing), reversible competitive inhibition
2
Q
Action
A
Blocks both the sympathetic nervous system and the parasympathetic nervous system. It acts as a non-depolarizing competitive antagonist at the nicotinic acetylcholine receptors
3
Q
Indications
A
Rarely used but sometimes for hypertensive crisis or in dissecting an aortic aneurism
4
Q
Toxicity
A
Very toxic and only used in emergency situations, orthostatic hypotension, urinary retention, constipation, impaired accomodation of lens of the eye
5
Q
Other Facts
A
Short acting, IV, does not cross BBB
