Primary Hyperparathyroidism Flashcards

1
Q

In exams, what is the common scenario in which the patient presents?

A

Elderly female with unquenching thirst.

Inappropriately normal or raised parathyroid hormone level.

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2
Q

What are the most common causes of hyperparathyroidism?

A
  1. 80%: solitary adenoma
  2. 15%: hyperplasia
  3. 4%: multiple adenoma
  4. 1%: carcinoma
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3
Q

What are some common features of hyperparathyroidism?

A
  • polydipsia, polyuria
  • peptic ulceration
  • constipation
  • pancreatitis
  • bone pain/fracture
  • renal stones
  • depression
  • hypertension
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4
Q

what 2 conditions is primary hyperparathyroidism associated with?

A
  1. Hypertension
  2. Multiple Endocrine Neoplasia (MEN 1 & MEN 2)
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5
Q

How do you treat primary hyperparathyroidism?

A

Parathyroidectomy

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6
Q

How would you investigate primary hyperparathyroidism and what would you find?

A
  • Raised calcium and low phosphate
  • PTH may be raised or normal
  • Technetium-MIBI subtraction scan
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