Thyroid Eye Disease Flashcards

1
Q

Describe the pathophysiology of thyroid eye disease.

A

Retro-orbital inflammation due to glycosaminoglycan and collage deposition in the muscles.

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2
Q

What can you advise to prevent it?

A
  • Stop Smoking - most important factor
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3
Q

What hyperthyroid treatment can worsen eye disease>?

A

Radioiodine treatment

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4
Q

How can you manage thyroid eye disease?

A
  • Topical lubricants may be needed to help prevent corneal inflammation caused by exposure
  • Steroids
  • Radiotherapy
  • Surgery
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5
Q

When should someone with thyroid eye disease be referred to an opthalmologist?

A
  • Unexplained deterioration in vision
  • Awareness of change in intensity or quality of colour vision in one or both eyes
  • History of eye suddenly ‘popping out’ (globe subluxation)
  • Obvious corneal opacity
  • Cornea still visible when the eyelids are closed
  • Disc swelling
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6
Q

What are some features of thyroid eye disease?

A
  • Exophthalmos
  • Conjunctival oedema
  • Optic disc swelling
  • Ophthalmoplegia
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7
Q

If someone has the inability to close his eyes due to thyroid eye disease, what is a complication?

A

Sore, dry eyes.

If severe and untreated patients can be at risk of exposure keratopathy

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