EBV

Question 1

How do patient with EBV present?

Answer 1

Infectious Mononucleosis:

Fatigue

Malaise

Pharyngitis

Lymphadenopathy

Fever

Anorexia

Vomiting

Question 2

What do you think of in a patient with a rash and EBV?

Answer 2

The rash is the result of a penicillin reaction (likely given if strep is thought to be the cause of the pharyngitis)

Question 3

What are some DDx for EBV

Answer 3

CMV

Human Herpes virus 6 (HHV-6)

HIV seroconversion

Question 4

How is the diagnosis of EBV made?

Answer 4

EBV infection induces various EBV specific ab and non-specific heterophile ab (specific to multiple species)

These hereophile ab can be tested for using the:

• Paul-Bunnell test and Monospot test

Testing for the EBV specific ab can follow these

Question 5

How is EBV treated?

Answer 5

These is no specific treatment for EBV

Corticosteroids are indicated for haemolytic anaemia, thrombocytopenia, CNS involvement or extreme tonsillar enlargement

Question 6

What are some complications of IM?

Answer 6

Tonsillar enlargement

CNS involvement

Haemolytic anaemia

Thrombocytopenia