[45] Role of Genetics in Thermogenesis Flashcards
What role does genetics play in thermogenesis?
Genetics can influence individual variations in thermogenesis, affecting metabolic rate, body weight regulation, and adaptation to environmental temperatures.
What is the effect of genetic variations on thermogenesis?
Genetic variations can lead to differences in basal metabolic rate, non-shivering thermogenesis, and heat production.
How can genetics influence susceptibility to obesity through thermogenesis?
Some genetic variants may reduce thermogenesis, leading to a lower energy expenditure and increased susceptibility to weight gain and obesity.
How do genetic factors influence brown adipose tissue (BAT) and its role in thermogenesis?
Genetic factors can influence the amount, distribution, and activity of BAT, which plays a key role in non-shivering thermogenesis.
What is the role of uncoupling proteins (UCPs) in thermogenesis and how are they influenced by genetics?
UCPs, particularly UCP1, play a critical role in thermogenesis by facilitating heat production in BAT. Genetic variations in the genes coding for UCPs can affect their function and thermogenesis.
What is UCP1?
UCP1 is an uncoupling protein found primarily in BAT that facilitates heat production, playing a critical role in thermogenesis.
What is BAT?
BAT stands for brown adipose tissue, a type of body fat involved in burning energy and producing heat, hence playing a significant role in thermogenesis.
