Gastrointestinal 💩 WK 7 Flashcards
Xylazine
Anesthetic-alpha2 agonist
label emetic-Fe
Chlorpromazine
Antiemetic-Phenothiazine derivative tranquilizer
AR-sedation/ataxia/hypotension
Apomorphine
Emetic used in K9s
Morphine derivative
Stimulates dopamine receptors in the CRTZ
Class 2 controlled substance
AR-protracted vomiting/restlessness/depression
Metoclopramide
Antiemetic-pro kinetic agent Blocks dopamine receptors in CRTZ Administer often Increases gastric contraction/gastric emptying, strengthens cardiac sphincter AR-CNS behaviour/constipation
Diphenhydramine Hydrochloride
Antihistamine “Benadryl”
Off label antiemetic
Indic: motion sickness, pruritus, allergies
Dimenhydrinate
Antihistamine- off label for motion sickness
Odansetron
Antiemetic-chemotherapy
Maropitant Citrate
NK-1 receptor antagonist Antiemetic-neurokinin receptor antagonist Tx acute vomiting/ motion sickness Off label- Fe **caution in hepatic patients**
Cimetidine
Anti ulcer agent-H2 Blocker
Inhibits histamine@ H2 receptors of gastric parietal cells
AR-alter metabolism
Ranitidine
Anti ulcer Agent-H2 Blocker
Famotidine
Anti ulcer-H2 Blocker
More potent than cimetidine
Omeprazole
Anti ulcer-proton pump inhibitor
Inactivates enzymes-prevents acid secretion
AR-constipated/sedation/ileus/pancreatitis/CNS effects
Sucralfate
Anti ulcer
Gastromucosal protectant
Binds to surfaces of gastric ulcers
AR-constipation
Loperamide-Imodium
Opioid Analgesic-anti diarrheal
Increase segmental contraction/decrease intestinal secretion/enhance absorption
AR-constipation/ileus/sedation/CBS excitement
Metronidazole
Antiprotozoal
Synthetic antibacterial/antiprotozoal
Tx giardiasis/trichomonias/hepatic encephalopathy/ulcerative colitis
AR-anorexia/hepatotoxicity/neutropenia/vomiting/diarrhea
