Skin/Antiinfective 😷 WK 10 Flashcards

1
Q

Topical Gentamicin Sulfate

A

Antibacterial/Aminoglycoside
Topical anti microbial
do not use on ulcers/burns/damaged skin

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2
Q

Silver Sulfadiazine (SSD)

A

Antibacterial/Sulfinamide
Tx 2-3 degree burns/skin infections
AR-reduce granulation

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3
Q

Acetic Acid

A

Antiseptic
Tx skin infections (staph.pseud.malassezia)
AR-skin irritation m/redness

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4
Q

Chlorhexidine

A

Antiseptic
Residual effects
AR-eye damage/irritation/corneal ulcer

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5
Q

Iodine

A

Antiseptic
Will stain
AR-skin irritation

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6
Q

Topical Ketoconazole

A

Anti fungal
Tx dermatophytes & yeast
AR-skin irritation

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7
Q

Topical Miconazole

A

Anti fungal
Tx dermatophytes & yeast
AR-skin irritation

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8
Q

Nystatin

A

Anti fungal
Tx topical yeast lesions
AR-allergic

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9
Q

Salicyclic Acid

A

Anti fungal/Antipruritic/Antibacterial/keratoplastic/keratolytic
Tx seborrheic disorders
AR-skin irritation

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10
Q

Amitraz

A

Topical Antiparasitic
Tx general demodicosis
toxic to rabbits and cats
AR-sedation

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11
Q

Imidacloprid

A

Topical Antiparasitic
“Advantage”
Advantix toxic to cats

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12
Q

Permethrin

A

Antiparasitic
Adult insecticide/miticide
“Advantix”
toxic to cats

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13
Q

Pyrethrin

A

Topical Antiparasitic
Adult insecticide/miticide
Tx fleas/lice/ticks/cheyletiella
AR-from licking

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14
Q

Amikacin

A

Aminocyclitols
dogs only/will yellow overtime
Tx serious gram -ve infection
AR-ototoxic/nephrotoxic/vestibular effects in cats

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15
Q

Gentamicin

A
Aminocyclitols
Tx serious gram -ve infections 
Use IV
**caution in CRF patients**
AR-ototoxicity
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16
Q

Neomycin

A

Aminocyclitols
Topical tx for skin/eyes/ears, tx enteric infections
AR-increases liver enzymes/lethargy/dermatological effects/aggressive behaviour/myopathy

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17
Q

Cephalosporin

A

Group of broad spectrum semisynthetic antibiotics
1st/2nd/3rd/4th generations
AR-increase liver function/intermittent increase BUN & serum creatinine levels

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18
Q

Macrolides

A

Inhibit protein synthesis by penetrating cell wall and binding to ribosomes in bacteria
Broad spectrum
Excreted in bile

19
Q

Penicillin

A
Bactericidal
Inhibits mucopeptide synthesis
Systemic absorption minus CSF/joints/milk
Absorbed in stomach/sm.intestines
Kidney excretion 
**usual suspension**
20
Q

Amoxicillin & Clavulante

A

Penicillin
Irreversibly bonds to beta lactamases/penicillinases
Tx urinary/skin/soft tissue infections
AR-allergic/GI upset

21
Q

Tetracyclines

A

Bacteriostatic antibiotic
Time-dependant antibiotic
Inhibit protein synthesis/anti inflammatory/immunomodulating
will stain young animals teeth

22
Q

Doxycycline

A

Antibiotic-tetracycline

AR-vomit/diarrhea/anorexia

23
Q

Lincosamides

A

Broad spectrum antibiotic

do not use in rabbits/hamster/Guinea pig/equine

24
Q

Clindamycin

A

Lincosamide
Tx wound/abscess/osteomyelitis
AR-GI upset/esophageal stricture (Fe)

25
Q

Quinolones

A

Bactericidal
Prevents DNA synthesis
Well absorbed/distributed widely

26
Q

Ciprofloxacin

A

Quinolone
Low bioavailability
AR-hypersensitivity

27
Q

Enrofloxacin

A

Quinolone
Tx various aerobes
forbid extra label use
AR-GI distress/CNS stimulation/crystalluria/hypersensitivity

28
Q

Marbofloxacin

A

Quinolone
Tx aerobes
AR-GI distress/hypersensitivity

29
Q

Orbifloxacin

A

Quinolone
Tx bacterial infections
AR- GI upset

30
Q

Sulfonamide

A

Bacteriostatic
Prevents bacterial replication
Kidney excretion

31
Q

Sulfadiazine

A

Sulfonamide
Tx infections MRSA
AR-KCS/hypersensitivity/vomit/anorexia/diarrhea/fever/hemolytic anemia/PD&PU/neutophylic hepatitis/hypothyroidism

32
Q

Chloramphenicol

A

Antibacterial
Tx infections & anerobes
Residual drug

33
Q

Metronidazole

A

Antibacterial
Tx giardia
AR-neurological disorders/lethargy/weakness/neutropenia/hepatotoxicity/hematuria/vomit/diarrhea

34
Q

Amphotericin B

A

Anti fungal
dilute for IV
AR-nephrotoxicity/anorexia/seizure/anemia/cardiac arrest

35
Q

Griseofulvin

A

Anti fungal
Tx dermatophytosis
AR-anorexia/vomit/diarrhea/ataxia/depression/hepatotoxicity/neutropenia

36
Q

Ketoconazole

A

Anti fungal
caution on cats
AR-GI upset/hepatotoxicity

37
Q

Nystatin

A

Anti fungal
Tx oral/GI candida
AR-GI upset/hypersensitivity

38
Q

Lysine

A

Antiviral Amino Acid

mix w/food

39
Q

Alcohol

A

Disinfectant/Antiseptic

Inactivated by organic compounds

40
Q

Biguanide Compounds

A

Disinfectant “Chlorhexidine”

41
Q

Chlorine/Iodines

A

Bactericidal/antiviral/anti fungal
Halogens inactivate pathogens
AR-skin/eye irritation

42
Q

Topical Corticosteroids

A

Used in conjunction with other drugs to tx localized itching/inflammation
do not use in pregnant animals

43
Q

Formaldehyde

A

Disinfectant/Antiseptic
Noncorrosive
Tx bacteria, fungi, spores, viruses
carcinogenic to humans

44
Q

Quartenary Ammonium Compunds

A

Cationic Detergent

Dissolve lipids in cell walls/membranes