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Pathology (F) > Morphologic markers > Flashcards

Morphologic markers Flashcards

1
Q

Neurofibrillary tangles

A

Alzheimer’s disease

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2
Q

PsaMMoma bodies

A

Papillary thyroid CA
Serous cystadenoCA of ovaries
Meningioma
Mesothelioma

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3
Q

Foam cells

A

Atherosclerosis

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4
Q

Strawberry gallbladder

A

Cholesterolosis

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5
Q

Bread-and-butter appearance

A

Fibrinous pericarditis

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6
Q

Shaggy membrane of necrotic tissue (pseudomembrane)

A

Diphtheria
Esophageal carcinoma
Pseudomembranous colitis

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7
Q

Langhan’s type of giant cells

A

PTB

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8
Q

Foreign-body type of giant cells

A

Keloids

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9
Q

Lines of Zahn

A

Antemortem thrombosis

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10
Q

chicken fat

A

Postmortem thrombosis

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11
Q

Libman-Sacks endocarditis (sterile)

A

SLE

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12
Q

Virchow-Robin spaces

A

Gaucher disease

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13
Q

Zebra bodies

A

Niemann-Pick disease

Mucopolysaccharidoses

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14
Q

Balloon cells

A

Mucopolysaccharidoses

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15
Q 
Russell bodies
Flame cells
Mott cells
Dutcher bodies 
Rouleaux formation
A

Multiple myeloma

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16
Q

Reed-sternberg cells

A

Hodgkin’s lymphoma

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17
Q

Starry sky pattern: nuclear remnants are phagocytosed by interspersed macrophages w/ abundant clear cytoplasm

A

Burkitt’s Lymphoma

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18
Q

Cloverleaf or flower cells

A

Adult T-cell lymphoma

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19
Q

Smudge cells

A

CLL

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20
Q

Pseudo-Pelger-Hüet cells
Pawn ball megakaryocytes
Ringed sideroblasts

A

Myelodysplastic syndrome

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21
Q

Tear drop cells (dacryocytes)
Leukoerythroblastosis
Osteosclerosis
Splenomegaly

A

Primary myelofibrosis

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22
Q

Birbeck granules (tennis racket-like)

A

Langerhans cell hystiocytosis

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23
Q

Gandy-Gamma nodules

A

Congestive splenomegaly

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24
Q

Howell-Jolly bodies (post-splenectomy)

Spherocytes

A

Hereditary spherocytosis

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25
Q

Heinz bodies

Bite cells

A

G6PD

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26
Q

Sickled cells
Codocytes (target cells)
Reticulocytosis
Howell-Jolly bodies

A

Sickle cell anemia

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27
Q

Basophilic stippling
Anisocytosis, poikilocytosis
Target cells
Micorcytic, hypochromic anemia

A

Thalassemia

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28
Q

Echinocytes / Burr cells

Schistocytes

A

Microangiopathic hemolytic anemia

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29
Q

Walthard cell rests

A

Brenner tumor

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30
Q

Chocolate cyst

A

Endometriosis

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31
Q

Schiller-Duval bodies

A

Yolk sac tumor

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32
Q

Call-Exner bodies

A

Granulosa Cell Tumor

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33
Q

Flexner-Wintersteiner rosettes

A

Retinoblastoma

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34
Q

Drusen

Choroidal neovascularization

A

Age-related macular degeneration

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35
Q

Hunner ulcers

A

Interstitial cystitis

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36
Q

Michaelis-Gutmann bodies

A

Malacoplakia

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37
Q

Erythroplasia of Qeyrat

A

Bowen disease

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38
Q

Schiller-Duval bodies

A

Yolk sac tumor

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39
Q

Helter-skelter collection of differentiated cells

A

Teratoma

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40
Q

Crystalloids of Reinke

A

Leydig cell tumor

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41
Q

Crystalloids of Charcot-Bottcher

A

Sertoli cell tumor

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42
Q

Hürthle cells

A

Hashimoto thyroiditis

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43
Q

Orphan Annie Nuclei

Psammoma body

A

Papillary thyroid carcinoma

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44
Q

Water-clear cell hyperplasia

A

Parathyroid hyperplasia

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45
Q

Kimmelstiel-Wilson nodules

A

Nodular glomerulosclerosis (DM)

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46
Q

Renal papillary necrosis

A

Pyelonephritis

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47
Q

Nesidioblastosis
Giant islet cells
Amyloid deposits

A

Insulinoma

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48
Q

Necrolytic migratory erythema

A

a-cell tumors (glucagonomas)

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49
Q

Crooke hyaline change

A

Cushing syndrome

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50
Q

Spirinolactone bodies

A

Conn syndrome/ aldosterone-producing adenomas

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51
Q

Erlenmeyer flask deformity

A

Osteopetrosis

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52
Q

Mosaic pattern (jigsaw puzzle) of lamellar bone

A

Paget Disease of the bone

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53
Q

Nidus formation

A

Osteoid osteoma

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54
Q

Homer-Wright rosettes

Onion-skin appearance of bone

A

Ewing Sarcoma

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55
Q

Ragged red fibers

Parking lot inclusion

A

Mitochondrial myopathy

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56
Q

Heliotrope rash

Gottron lesions

A

Dermatomyositis

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57
Q

Duret hemorrhages

Kernohan’s notch

A

Transtentorial herniation

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58
Q

Döhle bodies (toxic granules)

A

Sepsis

Other high inflamm states (assoc w/ leukocytosis)

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59
Q

Paracortical hyperplasia

A

Chronic lymphadenitis

assoc w/ EBV infx and phenytoin

60
Q

Centroblasts
Centrocytes
Tingible-body macrophages

A

Follicular hyperplasia

61
Q

Sinus histiocytosis (inc in # of size cells lining lymphatic sinusoids)

A

Breast CA

62
Q

Popcorn cells

Reed-Sternberg cells

A

Hodgkin’s Lymphoma

63
Q

Sézary-Lutzner cells

Pautrier microabscesses

A

Mycosis fungoides

64
Q

Hypoplasia of the arcuate nucleus
Hepatic extramedullary hematopoiesis
Periadrenal brown fat

A

SIDS

65
Q

Port-wine stains

A

Hemangioma

66
Q

Homer-Wright pseudorosettes
Neuropil
Blueberry muffin baby

A

Neuroblastoma

67
Q

Blueberry muffin

A

Neuroblastoma
Congenital Rubella Syndrome
CMV infx

68
Q

Homer-Wright Rosette

A

Neuroblastoma
Medulloblastima
Primitive Neuroectodermal Tumors (PNET)

69
Q

Flexner-Wintersteiner Rosette

A

Retinoblastoma

70
Q

True ependymal rosette

A

Ependymoma

71
Q

Perivascular pseudorosette

A 
Ependymoma
Medulloblastoma
PNET
Central neurocytom
Glioblastoma
72
Q

Lead lines
Microcytic, hypochromic anemia
Saturnine gout

A

Lead poisoning

73
Q

Milk and roses complexion

Mee’s lines

A

Arsenic poisoning

74
Q

Ophthalmoplegia
Ataxia
Confabulation

A

Chronic alcoholism

Wernicke-Korsakoff syndrome

75
Q

Marjolin ulcers (overturned burn edges)

A

Squamous cell carcinoma of the skin

76
Q

Trench foot

A

Hypothermia

77
Q

Flag sign

Flaky paint appearance

A

Kwashiorkor

78
Q

Russel’s sign

calluses on the back of the hands

A

Bulimia Nervosa

79
Q

Nyctalopia
Xerophthalmia
Keratomalacia

A

Vitamin A deficiency

80
Q

Pseudotumor cerebri
Hepatitis
Bone pains

A

Vitamin A toxicity

81
Q 
Craniotabes
Genu varum
Rachitic rosary
Pigeon chest deformity
Tetany
A

Vitamin D deficiency

82
Q

HyperCa

Renal calculi

A

Vitamin D toxicity

83
Q

Acrodermatitis enterohepatica
Diarrhea
Growth retardation

A

Zinc deficiency

84
Q

Keshan disease

A

Selenium deficiency

85
Q

Warthin-Finkeldey cells

Koplik spots

A

Measles

86
Q

Cowdry type A bodies

A

Herpes simplex infx

87
Q

Ramsay Hunt syndrome

A

Varicella

88
Q

Owl’s eye inclusions (intranuclear basophilic inclusions)

Heterophil (-) mononucleosis

A

CMV infx

89
Q

Downey cells

Heterophil (+) mononucleosis

A

EBV infx

90
Q

Pastia’s lines

Strawberry tongue

A

Scarlet fever

91
Q

Tumbling motility

A

Listeria monocytogenes

92
Q

Swarming motility

A

Proteus mirabilis

93
Q

Shooting star motility

A

Falling leaf motility

94
Q

Boxcar-shaped gram (+) extracellular bacteria in chains

A

Bacillus anthracis

95
Q

Slender beaded gram (+) arrranged in branching filaments
(+) Fite-Faraco
(-) granulomas

A

Nocardia asteroides

96
Q

Haze of bacteria entangles with cilia on bronchial epith

A

Bordetella pertussis

97
Q

Fleur-de-lis pattern

Perivascular blue haze

A

Pseudomonas aeruginosa

98
Q

Superficial zone of neutrophilic debris w/ underlying granulation tissue (painful genitla ulcer)

A

Chancroid (Hemophilus ducreyi)

99
Q

Donovan bodies on Warthin-starry stain

Pseudoepitheliomatous hyperplasia

A

Klebsiella granulomatis

100
Q

Ranke’s complex
Simon’s focus
Ghon’s focus
Langhan’s type of giant cells

A

Mycobacterium tuberculosis

101
Q 
Lepra cells (red snappers)
Globi (multibacillary masses of acid-fast bacilli)
A

Lepromatous leprosy

102
Q

Gummas

Endarteritis

A

Tertiary syphilis

103
Q

Erythrophagocytosis

A

Borrelia recurrentis

Entamoeba histolytica

104
Q 
Erythema chronicum migrans
Lyme arthritis (onion skin-like lesions)
A

Borrelia burgdorferi

105
Q

Stellate abscesses

A

Lymphagranuloma venereum (Chlamydia trachomatis)

106
Q

Amount of tissue necrosis disproportionate to neutrophils and bacteria

A

Clostridium perfringens cellulitis

107
Q

typhus nodules

focal microglial proliferations w/ mixed T lymphocytes

A

Typhus fever (Rickettsia)

108
Q

Soap bubble lesions

yeasts grow in meninges and expand Virchow-Robin spaces

A

Cryptococcus neoformans

109
Q

Hyphae within cavitations

Necrotizing pneumonia

A

Aspergillus fumigatus

110
Q

Necrotizing pneumonia

A

Aspergillus
Yersinia
Staph
Pseudomonas

111
Q

Durck granulomas (ring hemorrhages)

A

Malaria

112
Q

Schuffner’s dots

A

P. vivax and ovale

113
Q

Ziemann’s dots

A

P. malariae

114
Q

Maurer’s dots

A

P. falciparum

115
Q

Maltese cross pattern

A

Babesia microti

116
Q 
Mott cells
Capillary loops (parasites concentrate in choroid plexus and glomeruli)
A

Trypanosomiasis (African Sleeping Sickness)

117
Q

Romaña’s sign (unilat periorbital edema)

Megacolon

A

Chagas disease (T. cruzi)

118
Q

Nurse cells

A

Trichinella spiralis

119
Q

Pipe-stem fibrosis

A

Severe schistosomiasis

120
Q

Meyers-Kouvenaar bodies

A

Tropical pulmonary eosinophilia (Filariasis)

121
Q

Lizard skin
Onchocercoma
Sclerosing keratitis (river blindness)

A

Onchocerca volvulus

122
Q 
Linitis plastica (leather bottle appearance)
Desmoplastic rxn
A

Gastric adenoCA

123
Q

Salt-and-pepper chromatin

A

Carcinoid tumor

Small cell lung CA

124
Q

Intraepith lymphocytosis
Crypt hyperplasia
Villous atrophy

A

Celiac disease

125
Q

Crypt abscesses

Cryptitis

A

Campylobacter jejuni

126
Q

Enlargement of Peyer’s patches
Oval ulcers
Neutrophilic infiltration of lamina propria

A

Typhoid fever (Salmonella typhi)

127
Q

PAS (+), diastase resistant granules
Distended foamy macrophages
Gram (+) actinomycete, Tropheryma whippelii
Malabsorptive diarrhea d/t impaired lymphatic transport

A

Whipple’s disease

128
Q

Paneth cell metaplasia
Noncaseating granulomas
Crypt abscesses

A

Crohn’s disease

129
Q

Backwash ileitis
Mucosal atrophy
(-) Mural thickening

A

Ulcerative colitis

130
Q

Thin diverticular walls (absent muscularis propria)

Epiploic appendices

A

Sigmoid diverticulitis

131
Q

Arborizing networks

Hamartomatous polyps

A

Peutz-Jehgers syndrome

132
Q

Smooth nodular protrusions of mucosa

Serrated architecture

A

Hyperplastic polyps

133
Q

Epith dysplasia
Velvety texture
Pedunculated/ Sessile

A

Neoplastic polyps

134
Q

Dysplastic epithelium
Desmoplastic response
Mucin accumulation
Signet-ring cells

A

Colorectal adenoCA

135
Q

Ground-glass hepatocytes

A

Chronic Hepa B infx

136
Q

Lymphoid aggregates
Bile duct reactive changes
Steatosis

A

Chronic Hepa C infx

137
Q

Mallory bodies
Laennec cirrhosis
Hobnail appearance

A

Alcoholic hepatitis

138
Q

Weibel-Palade bodies

A

Endothelial cell

139
Q

Wire-loop capillaries

A

Type 4 lupus nephropathy

Diffuse proliferative

140
Q

Purpuric skin lesions in the extensor surfaces of extremities
(+) IgA deposits
1/3 -nephrotic

A

HSP

141
Q

Immune complex nephritis initiated by bacterial Ag

A

Bacterial endocarditis

142
Q

Protein level in UA in nephrotic syndrome

A

> 3.5 g / 24h

143
Q

Papillary necrosis

A

Pyelonephritis

144
Q

Kimmelsteil-Wilson nodules (nodular glomerulosclerosis)
Fibrin caps
Capsular drops

A

DM nephropathy

145
Q

Tamm-Horsfall protein

(+) hyaline and granular cast

A

ATN

146
Q

Bence Jones protein

Tamm Horsfall proteins

A

Multiple myeloma

Pathology (F) (20 decks)

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