Development aspects of Lung Disease Flashcards
How many stages are there to lung development
5
name the 5 stages (in order) to lung development
embryonic pseudo-glandular canalicular saccular alveolar
what happens in the embryonic stage
development of the lung buds
what happens in the pseudoglandular phase
branching of the respiratory tree occurs
what happens in the canalicular phase
epithelial differentiation
lumen of the bronchi increase in size
respiratory bronchial and alveolar ducts develop
tissue becomes vascular
what happens in the terminal sac phase
expansion of air spaces
surfactant detectable
define laryngeal stenosis
narrowing of the airways
define pulmonary agenesis
agenesis= failure of an organ to develope
pulmonary agenesis is complete absence of a lung or lobe and its bronchi
define tracheosophagal fistula
abnormal connection between the esophagus and the trachea
define pulmonary sequestration
accessory lung, a segment or lobe of the lung tissue has no bronchial communication with the normal tracheobronchial tree.
define transient tachypnea of the newborn (TNN)
wet lung, baby that still has fluid in its lungs therefore makes it difficult to inhale O2 baby breathes harder and faster to get enough oxygen
define hypoplasia
incomplete development of a tissue or organ
what are glucocorticoids
any group of corticosteroids involved in the metabolism of carbohydrates, proteins and fats and have anti-inflammatory activity
define Bronchiolitis
viral lower respiratory tract infection that infects babies and younger children. inflammation of the bronchioles
what are common pediatric origins of adult lung disease
Antenatal: in utero nicotine exposure
poor nutrition
premature
all above influenced by gene-environment interactions
