Pathology of Pulmonary Tract Infection Flashcards

1
Q

what are some common upper respiratory tract infections

A

coryza
acute laryngotracheobronchitis
laryngitis
acute epiglottiis

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2
Q

What is so dangerous about acute epiglottitis

A

swelling will put at risk the opening to the trachea therefore medical emergency can die as a result of sufication

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3
Q

what are some common lower respiratory tract infections

A

bronchitis
Pneumonia
bronchiolotis

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4
Q

What are the respiratory tracts defense mechanisms

A

MMES
general immune system humoral and cell mediated
respiratiry tract secretions

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5
Q

define cytopathic

A

structural changes in host cells that are caused by viral invasion

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6
Q

the lower respiratory tract should be sterile, true or false

A

true

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7
Q

if the epithelium involved in the MMes gets damaged what repercussions could this have

A

no exit from the lungs for the MM escalator, leads to secondary infections and this is what kills most people

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8
Q

define hypostatic

A

accumulations of secretions in the lungs

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9
Q

what is bronchopnemonia

A

inflammation of the lungs, arising in the bronchi or bronchioles. spills out into the lungs.

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10
Q

define lobar Pneumonia

A

inflammation of the entire lobe of lung. 95% of cases caused by streptotococi

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11
Q

what is bronchiectasis

A

pathological dilation of bronchi due to sever infective episode

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12
Q

what are the symptoms of Bronchieactasis

A
persistent cough
abundant purulent foul sputum
haemoptysis
coarse crackles 
clubbing
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13
Q

define hypoxaemia

A

abnormally low levels of oxygen in the blood

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14
Q

define cor pulmonale

A

Cor pulmonale refers to the altered structure of the right ventricle that results from pulmonary hypertension that is associated with diseases of the lung

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15
Q

Lung conditions that cause a low blood oxygen level in the blood over a long time can also lead to cor pulmonale. true or false

A

true

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16
Q

what bacteria and virus is acute epiglottis usually caused by

A

Bacteria- Group A beta-haemolytic streptococci

Virus- Haemophilus influenzae

17
Q

what are the different aetiology classifications of pneumonia

A
  1. community
  2. nosocomial (hospital)
  3. Pneumonia in the immunocompromised
  4. atypical pneumonia
  5. aspiration pneumonia
  6. recurrent pneumonia
18
Q

what can be complications of pneumonia

A

pleurisy, pleural effusion
organisation
lung abscess
bronchiectasis

19
Q

what are the 4 abnormal states associated with hypoxaemia

A

ventilation/perfusion imbalance
diffusion impairment
alveolar hypoventilation
shunt

20
Q

what is the commonest cause of hyoxaemia encountered clinically

A

low V/Q ( V/Q mismatch)

21
Q

what is the difference between a ventilation/perfusion abnormality and shunt

A

in V/Q there is some ventilation of abnormal alveoli just not enough
in shunt there is no ventilation of abnormal alveoli