L6

Question 1

Strep
Gram
oxygen
Catalase
cocci

Answer 1

Gram +
Facultative anaerobe
Catalase negative
Chains/diplococci

Question 2

Strep classification (3)

Answer 2

Hemolysis pattern
Lancefield group
Species

Question 3

Lancefield group

Answer 3

Based on cell wall carb antigens
A-U
Latex particles with antibodies are used to test which antigen

Question 4

Hemolysis patterns
alpha
beta
gamma

Answer 4

alpha: partial hemolysis and green discoloration of hemoglobin
Beta: clear zone of complete hemolysis
Gamma: no zone of clearing

Question 5

Which group of step is strictly human

Answer 5

Group A (beta)

Question 6

Strep throat

Answer 6

S. Pyogenese

Question 7

Suppurative infections

Answer 7

Pharyngitis
scarlet fever
Impetigo

Question 8

Non suppurative infections

Answer 8

Acute glomerulonephritis

Rheumatic fever

Question 9

Acute Rheumatic fever

Answer 9

Must invoke immune response
Non suppurative
Heart and joint inflammation
Valvular scarring

Question 10

What is the only site of infection followed by ARF

Answer 10

Pharynx

1-4 weeks post strep throat

Question 11

Group A infections live in

Answer 11

skin and mucous membranes

Question 12

Group A infection Entry

Bind to epithelial cells using

Answer 12

Cant penetrate intact skin

Adhesins

Question 13

Group A Adhesins

Binds to

Answer 13

Lipoteichoic Acid LTA binds to fibronectin
Protein F: high affinity fibronectin binding protein
M protein: keratinocyte adhesin

Question 14

Group A Spread

Answer 14

Skin and mucous remains localized

Deep tissue has rapid spread

Question 15

Streptokinase

Answer 15

degrades fibrin to reduce blood clots

Question 16

Group A multiplication

Antiphagocytic factors

Answer 16

M protein (Most important)
Hyaluronic acid capsule
C5a Peptidase

Question 17

M protein importance

Answer 17

Essential for
pathogenesis 
virulence
Binds several serum proteins
Inhibits opsonin formation by blocking proteins and complements

Question 18

Hyaluronic acid capsule

Answer 18

Makes strep slippery

Question 19

C5a Peptidase

Answer 19

inactivates phagocyte chemotaxin

Question 20

True or false: Hyaluronic Acid Capsule is the same as polysaccharaide capsule of staphylococci

Answer 20

FALSE

Question 21

Superantigens
Activity
Types

Answer 21

activate macrophages and cause T cells to release cytokines
SpeA SpeB SpeC
Responsible for red rash of scarlet feer

Question 22

Group B Strep

Location

Answer 22

Lower GI

Female genital tracts

Question 23

Group B strep capsule
Vs Group A
Which type is most prevelant

Answer 23

Polysaccharide capsule that is intigenic unlike hyaluronic capsule of GAS
Type III

Question 24

Group D Strep
Location
Virulence

Answer 24

Normal in GI and urinary tract

Low virulence

Question 25

Enterococci

why worlds toughest?

Answer 25

Grow in high salt,
not killed by penicillin
Resistant to most antibiotics
Synergism required to kill

Question 26

Nonenterococcal Group D

Survival

Answer 26

Does NOT grow in high salt

IS killed by penicilin

Question 27

Nonentercoccal most common for human disease

Answer 27

S. Bovis

Question 28

Viridans streptococci

alpha,beta,gama

Answer 28

Alpha

30-60% of oropharyngeal flora

Question 29

Responsible for caries

Answer 29

Viridans Streptococci mutans

Viridans Streptococci sobrinus

Question 30

S. mutans cause of caries

Answer 30

Ferment sugar to lactic acid

AND thrive in low pH

Question 31

Glucosyltransferases convert sucrose to

Answer 31

Glucan

Question 32

Competence

Answer 32

Bacteria taking up DNA from environment