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ORAL PATHOLOGY! > Exam 2-Non-Neoplastic Proliferations > Flashcards

Exam 2-Non-Neoplastic Proliferations Flashcards

1
Q

Patients commonly present with swelling (_________). This can be the result of _________, a ______ lesion or a ________ lesion (either benign or malignant).

A

TUM–E–faction…inflammation… reactive…. neoplastic

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2
Q

_______ tumors are usually the result of hyperplasia which is due to an increase in the number of normal cells

A

REACTIVE

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3
Q

Reactive tumors are usually the result of _________ which is due to an increase in the number of normal cells

A

hyperplasia

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4
Q

Reactive tumors are usually the result of hyperplasia which is due to an increase in the number of ______ cells

A

NORMAL

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5
Q

While reactive tumors can become quite large, they are not considered to have “unlimited _________” like neoplasms

A

growth potential

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6
Q

reactive tumors are thought to be the result of the body’s reaction to a stimulus (often ______ irritation)

A

physical

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7
Q

Reactive lesions constitute about ___% of all lesions biopsied in a dental office.

A

20%

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8
Q

________ lesions constitute about 20% of all lesions biopsied in a dental office.

A

REACTIVE

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9
Q

_______: Hyperplasia of fibrous connective tissue

A

fibroma

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10
Q

WHAT IS THE MOST COMMON TUMOR OF THE ORAL MUCOSA?

A

FIBROMA!!

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11
Q

What am I describing?? usually sessile, smooth surfaced, normal color, asymptomatic

A

Fibroma

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12
Q

Where are fibroma’s most often found?

A

Cheek, but can be found everywhere

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13
Q

What is the variant that you DON’T want to confuse with a giant cell granuloma?

A

Giant Cell Fibroma

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14
Q

What can a Giant Cell Fibroma be sometimes confused with in name? WHAT ABOUT CLINICALLY??

A

A Giant cell granuloma…Clincially: Papilloma

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15
Q

________: “papillary” tumor of fibrous connective tissue containing plump, stellate and often bi or trinucleated fibroblasts

A

Giant Cell Fibroma!

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16
Q

Which age group is most susceptible to Giant Cell fibromas?

A

Children

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17
Q

What are the two most common areas to find a Giant Cell Fibroma?

A
  1. Gingiva 2.Tongue
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18
Q

What is a reactive, fibroblastic lesion of PDL?

A

Peripheral Odontogenic (Ossifying) Fibroma

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19
Q

What is the most common age range for a Peripheral Odontogenic (Ossifying) Fibroma?

A

10-30 years old

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20
Q

Where is the ONLY place a Peripheral odontogenic (ossifying) fibroma occurs?

A

The gingiva (PDL)

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21
Q

What are the symptoms associated with a Peripheral Odontogenic (Ossifying) Fibroma?

A

HAHA GOT YA! NONE…Asymptomatic

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22
Q

What could I be describing??: pedunculated or sessile mass ± red ± ulceration

A

Peripheral Odontogenic (Ossifying) Fibroma

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23
Q

What am I describing?: Histology: Cellular fibroblastic lesion with bone and/or cementum and/or dystrophic calcification

A

Peripheral Odontogenic (Ossifying) fibroma

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24
Q

What is the treatment for a Peripheral Odontogenic (Ossifying) Fibroma?

A

Excision, including superficial PDL

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25
Q

WHICH REACTIVE GINGIVAL LESION HAS HIGHEST RECURRENCE RATE? What is the rate?

A

Peripheral Odontogenic (Ossifying) Fibroma…15-20% recurrence rate

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26
Q

What is another name for Inflammatory Fibrous Hyperplasia?

A

Epulis Fissuratum

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27
Q

What are reactive folds of hyperplastic fibrous connective tissue along border of ill-fitting, over extend denture (2 names please)

A

1.Inflammatory Fibrous Hyperplasia 2.Epulis Fissuratum

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28
Q

What is the histology of an epulis fissuratum (inflammatory fibrous hyperplasia)?

A

lol…fibrous hyperplasia and inflammation (I wonder how it got its name??)

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29
Q

What is the treatment for Inflammatory fibrous hyperplasia (aka. epilus fissuratum)

A

excision and reline (or remake) the denture

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30
Q

What is another name for Inflammatory Papillary Hyperplasia?

A

Papillamatosis

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31
Q

What is classified as a hyperplastic response of palatal mucosa to ill-fitting denture

A

Inflammatory Papillary Hyperplasia (papillamatosis)

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32
Q

What is the fancy term for the histology of a Inflammatory Papillary Hyperplasia?

A

Pseudo-Epithel-io-matous Hyperplasia (PEH)

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33
Q

What is the treatment for Inflammatory Papillary Hyperplasia?

A

Excise, remake/reline

34
Q

What is a Tumor of well vascularized fibrous connective tissue containing numerous multinucleated giant cells?

A

Peripheral Giant Cell Granuloma

35
Q

What is the most common site for a Peripheral Giant Cell Granuloma?

A

the anterior gingiva

36
Q

What is the typical age for the occurrence of a peripheral giant cell granuloma? What are the typical symptoms?

A

any age, asymptomatic

37
Q

Which type of lesion can be a usually reddish-brown-purple pedunculated or sessile mass

A

Peripheral Giant Cell Granuloma

38
Q

Who is affected more by peripheral giant cell granulomas: males or females?

A

females 2:1!!

39
Q

Which type of lesion may produce cupping resorption of underlying bone?

A

Peripheral Giant Cell Granuloma

40
Q

Treatment of a Peripheral Giant Cell Granuloma: Excision and removal of irritants, may DO WHAT?

A

RECUR!

41
Q

Why is a pyogenic granuloma a misnomer?

A

because its not a pus producing lesion…its a reactive lesion made of granulation tissue

42
Q

What lesion is reddish, ulcerated pedunculated or sessile mass?

A

Pyogenic Granuloma

43
Q

What are the most common age ranges for a Pyogenic Granuloma and where is the most common site for one? WHAT ARE THE SYMPTOMS?

A

20-40 years old and on the gingiva…Asymptomatic but may bleed easily (I THINK I HAVE ONE OF THESE!!)

44
Q

What lesion has the nickname of “pregnancy tumor”?

A

Pyogenic Granuloma

45
Q

What is a pyogenic granuloma called in an extortion socket?

A

Epilus Granulomatosa

46
Q

This is the histology of WHAT type of non-neoplastic proliferation???: Hyperplastic granulation tissue, fibroblasts with delicate collagen, endothelial cells + capillaries and dilated larger vessels

A

Pyo-genic Granuloma

47
Q

Can a pyogenic granuloma recur if it is excised?

A

Yep!

48
Q

What is another name for a gum boil?

A

“Parulis”

49
Q

Hmmm…WTF am I talkin’ bout? Can occur anywhere but on gingiva, it represents draining from a source of odontogenic infection of either pulpal or periodontal origin pus (purulence, suppuration) = bacterial infection

A

A Parulis/Gum Boil

50
Q

Holy shit, what is the 5 word name for this indication: Localized hyperplasia presumably from externalized sulcular epithelium on gingiva….(typically in JUVENILES!)

A

Localized juvenile spongiotic gingival hyperplasia

51
Q

Localized juvenile spongiotic gingival hyperplasia: ALMOST EXCLUSIVELY in what age range and what sex?

A

10-30 y/o and 2:1 female

52
Q

Localized juvenile spongiotic gingival hyperplasia: almost all ________ gingiva, and which arch is more likely?

A

anterior….maxillary arch

53
Q

Localized juvenile spongiotic gingival hyperplasia: WHAT COLOR?… often _______ gingival lesions

A

RED…. papillary

54
Q

WHO AM I? (I don’t know) Papillary proliferation of inflamed epithelium with intercellular edema (spongiosis)

A

Localized juvenile spongiotic gingival hyperplasia:

55
Q

What is an Overgrowth of blood vessels ?

A

Hemangioma

56
Q

(________– localized overgrowth of tissues native to the part, often developmental)

A

hamartoma

57
Q

HEMANGEOMA is a rapid proliferation of WHAT TYPE OF cells at birth or shortly thereafter, characteristically INVOLUTE (whatever the f that means)

A

ENDOTHELIAL

58
Q

**What is the most common tumor of infancy?!?

A

Hemangioma (5-10%) incidence

59
Q

What sex is more likely to have a HE-MAN-geoma? What % of these are in the Head and Neck?

A

Females (3:1)…60% are Head and Neck

60
Q

When is the MOST likely age range for a HE-MAN-gioma to develop? They are 90% developed at what age?

A

0-5 years…90% by age 10

61
Q

Is a He-Man-gioma congenital?

A

RARELY congenital!

62
Q

What is a reddish to purple mass lesions that tend to blanch with pressure?

A

Hemangioma

63
Q

What is UNIQUE about an ORAL hemangioma?

A

they develop later in life and don’t involute

64
Q

Which NON-Neoplastic Proliferation can occur in BONE, often multilocular or soap bubble appearance (why you aspirate before bone biopsy)???

A

Hemangioma

65
Q

Which non-neoplastic proliferation histologically has Endothelial cell proliferation with formation of small capillaries (capillary) or larger dilated vascular spaces (cavernous)?

A

Hemangioma

66
Q

What non-neoplastic proliferation is treated via these methods: Natural history is INVOLUTION laser pulse, excision, sclerosing agents, steroids both intralesional and systemic, propranolol

A

Hemangioma

67
Q

WTF is this?? Nonhereditary developmental, congenital condition characterized by vascular proliferation of brain and face usually along distribution of ophthalmic branch of the trigeminal nerve??

A

STURGE-WEBER ANGIO-MAT-OSIS

68
Q

What is the scientific name for Sturge-Weber Angiomatosis? (think of its location!!)

A

Encehpalo-Trigeminal Angiomatosis

69
Q

Is Sturge-Weber hereditary?

A

Non-hereditary

70
Q

Is Sturge-Weber congentical?

A

Yes, it is congenital

71
Q

THIS IS….AWESOME!!!! Sturge-Weber and port wine stains are due to somatic activation mutation in _____ which encodes Gαq, a member of the q class of ________ alpha subunits that mediates signals between ________–coupled receptors and downstream effectors. The difference is when and where the mutation occurs

A

GNAQ….G-Protein..G-PROTEIN

72
Q

Sturge-Weber: Large WHAT COLOR lesions –identical clinically to ________ stains, (IPSILATERAL or CONTRALATERAL) oral mucosal involvement common leptomingeal angiomas of cerebral cortex

A

Purplish…port-wine…IPSILATERAL

73
Q

You better not get this shiz wrong: What is a developmental overgrowth of lymphatic vessels?

A

Lymphangioma

74
Q

Where are the most common regions for lymphangioma and what age are they most common in?

A

head and neck….0-5 years

75
Q

Where is the most common place for a lymphangioma in the mouth?

A

on the TONGUE!!

76
Q

What type of tongue pathology can be the result of lymphangioma

A

MACROglossia

77
Q

A superficial lymphangioma is likely to have a _____ surface with translucent vesicles.

A

pebbly

78
Q

Are deeper lymphangiomas of the tongue more concentrated or more diffuse?

A

more diffuse

79
Q

What is the VARIANT of a Lymphangioma that infiltrates and becomes VERY large (↑ neck)?

A

Cystic Hy-GRO-ma

80
Q

This is the Histology of WHAT? Proliferation of thin walled lymphatic vessels capillary sized, Dilated (cavernous) or cystically dilated (cystic hygroma)

A

Lymphangioma

81
Q

This is the treatment for WHICH non-neoplastic proliferation: Lesions don’t involute, Excision, Deeper ones often recur, Sclerosing agents

A

Lymphangioma

ORAL PATHOLOGY! (40 decks)

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