loop of Henle Flashcards
what parts of the nephron are in the medulla
vasa recta
loop of henle
collecting duct
what is the function of ADH
allows the distal tubule and collecting ducts to become permeable to water and so reabsorbed
how are ions absorbed across the thin ascending loop of Henle
passive absorption
how are ions reabsorbed in the thick ascending loop
Na- active transport
cotransport of postassium, chloride and other ions
what is the renal papilla
where the renal pyramids in the medulla enter into the minor calyx
what is normal osmolarity of the ECF
300 mOm/L
how does ecf change in the kidney
it is reduced to 100 mOmL in the dct
how concentrated can urine be
1200 mosm/l. This is the same concentration as the renal medulla.
what is the difference between the thick and thin ascending loops
passive absorption- thin
active transport of sodium and co transport of K and Cl- thick
what is the descending loop impermeable to
salt
what is the ascending loop impermeable to
water
what is the purpose of the loop of henle
counter current multiplier that generates a concentration gradient
what is the purpose of the thick ascending loop
establishes a concentration gradient between the interstitial fluid and the descending loop which causes water to diffuse out of the descending loop
where is most water absorbed from the collecting duct
cortical region
how does urea contribute to concentrating urine
ADH activated urea transporters move urea out of the collecting duct into the interstitium
this can move into the loop of Henle and can recirculate
this helps concentrate urea and forms the hyperosmotic renal medulla
partly due to slow movement in the tubules
