5/30/25 Endocrine Hormones Definitions Flashcards
(47 cards)
What occurs when two hormones have the same effect on the same tissue and their combined effects are amplified? (example would be E and NE have an additive effect on HR)
Synergistic Effect
What occurs when one hormone must be present in order for another hormone to exert its full effect? (thyroid hormone must be present for reproductive hormones to promote timely development of the reproductive system)
Permissive effect
What occurs when one hormone opposes the action of another hormone? (example PTH increases blood calcium, calcitonin decreases blood calcium)
Antagonistic effect
What are most hormones made of?
Amino acids
What are steroid based hormones made from?
Cholesterol
What hormone type is lipid soluble?
Steroid based hormones
What types of hormones are steroid hormones?
Gonadal (androgens like testosterone, estrogen, progesterone) and Adrenocortical (cortisol and aldosterone)
What hormone type is water soluble?
amino acid hormones (besides thyroid hormones)
What is the overall function of water soluble hormones (Amino acid based)?
They bind to a receptor that is coupled to a regulatory protein on the plasma membrane. This activates a secondary messenger to initiate a cell response (quick)
What is the overall function of lipid-soluble hormones?
Bind to intracellular receptors and alter transcription or translation to mediate cell response (slow)
Difference between neurotransmitters and hormones
Neurotransmitters do not travel in the bloodstream, but hormones do.
What local chemical messenger exerts effects on the same cells that secrete them?
Autocrine messengers
What local chemical messenger exerts their effects on nearby cells other than themselves?
Paracrine messengers
What glands release hormones directly into the bloodstream?
Endocrine glands
What glands produce non hormonal substances and release through a duct to a membrane surface?
Exocrine glands
Describe negative feedback loops
The response to a stimulus is to oppose or reduce the change that triggered it, thus bringing the variable back towards the set point
Describe positive feedback loops?
The response amplifies or strengthens the initial stimulus, pushing the variable further away from the set point
What is a primary disorder?
an excess or deficiency of secretion by the target gland
What is a secondary disorder?
An excess or deficiency of secretion by the pituitary gland
What is a tertiary disorder?
An excess or deficiency of secretion by the hypothalamus
Hypothyroidism
Low T3 and T4, high TSH
Hyperthyroidism
High T3 and T4, low TSH
Primary hypothyroidism
High levels of thyroid hormone secondary to the dysfunction of the thyroid gland
Secondary hypothyroidism
Low levels of thyroid hormone secondary to dysfunction of the pituitary