5. Digestive and Excretory Flashcards

(57 cards)

1
Q

is there digestion in the esophagus?

A

no

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2
Q

where and how does digestion begin?

A

in the mouth
carbs digested by alpha amylase

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3
Q

pepsin

A

catalyzes breakdown of protein the stomach

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4
Q

exocrine cells of the stomach

A

mucous
chief (peptic)
parietal
G cells

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5
Q

chief cells secrete…

A

pepsinogen

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6
Q

parietal cells secrete…

A

HCl through active transport

intrinsic factor (helps ileum absorb B12)

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7
Q

G cells secrete…

A

gastrin

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8
Q

function of gastrin

A

stimulates parietal cells to secrete HCl

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9
Q

G cells are activated by…

A

presence of polypeptides in stomach
distension
parasympathetic

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10
Q

most digestion occurs in the…

A

duodenum

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11
Q

lacteal

A

lymph vessel responsible for absorbing fats

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12
Q

brush border

A

on lumen side of villi
contains membrane bound digestive enzymes

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13
Q

goblet cells

A

secrete mucus that help protect the brush border

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14
Q

trypsin/chymotrypsin

A

degrade proteins

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15
Q

pancreatic amylase

A

degrades carbs

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16
Q

lipase

A

degrades fats (triglycerides)

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17
Q

bile

A

unclumps fat
produced in liver and stored in gall bladder

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18
Q

parts of the large intestine

A

ascending
transverse
descending
sigmoid
rectum

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19
Q

major functions of large intestine

A

water and electrolyte absorption

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20
Q

gastrin site, stimulus, target, effects

A

site: stomach
stimulus: ACh from vagus nerve
target: stomach
effects: production of HCl

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21
Q

secretin site, stimulus, target, effects

A

site: duodenum
stimulus: arrival of HCl in chyme
target: pancreas
effects: secretion of sodium bicarbonate and enzymes

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22
Q

gastric inhibitory polypeptide site, stimulus, target, effects

A

site: duodenum
stimulus: fat and protein in chyme
target: pancreas and stomach
effects: enzyme secretion (pancreas), decrease motor activity (stomach)

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23
Q

CCK site, stimulus, target, effects

A

site: duodenum
stimulus: arrival of fat digestates
target: pancreas and stomach
effects: enzyme secretion (pancreas), decrease motor activity (stomach)

24
Q

where does the conversion of glucose to fat take place?

A

adipocytes in the liver

25
how is glucose absorbed in the intestine?
by secondary active transport of sodium on the apical surface moves through the basolateral surface into the bloodstream to the liver using facilitated diffusion
26
how does fructose absorption differ?
does not need secondary active transport, facilitated diffusion only most is converted to glucose in the enterocyte
27
protein digestion
stomach: protein to polypeptide (pepsin) intestine: to amino acids (trypsin)
28
how is protein absorbed in the intestine?
depending on the polarity of the amino acid (could be facilitated diffusion or secondary active transport by sodium gradient) facilitated diffusion on basolateral surface into blood to the liver
29
fat digestion
bile and lipase work together in small intestine to emulsify into micelles to be shuttled to brush border
30
how is fat absorbed in the small intestine?
diffuse simply at apical surface as monolipids and fatty acids converted back to triglycerides at endoplasmic reticulum released as chylomicrons in exocytosis to the lacteal
31
albumin
protein that carries fatty acid molecules through the blood
32
liver function in carb metabolism
maintains glucose levels through gluconeogenesis, glycogenesis, release of glucose stores
33
liver function in fat metabolism
synthesizes bile converts carbs and proteins into fat oxidizes fatty acids for energy
34
what happens to blood pH when the liver mobilizes fats and proteins for energy?
decreases
35
liver function in protein metabolism
deaminates amino acids forms urea from ammonia in blood synthesizes fibrinogen, prothrombin, albumin
36
globulins
contain antibodies made by plasma cells
37
prothrombin and fibrinogen
clotting factors
38
constriction of the afferent arteriole will...
decrease blood flow and hydrostatic pressure resulting in less filtration
39
constriction of the efferent arteriole will...
increase hydrostatic pressure resulting in more filtration
40
fluid in Bowman's capsule is called
filtrate
41
path of filtrate through nephron
Bowman's capsule Proximal convoluted tubule Thin descending limb Thick ascending limb Distal convoluted tubule Collecting duct
42
counter-current multiplier mechanism
1. salt is pumped from filtrate to medulla 2. water is equilibrated 3. shift filtrate along the tube function is to concentrate urine
43
distal tubule
reabsorbs sodium and calcium ions while secreting potassium, hydrogen and bicarbonate
44
effect of aldosterone on distal tubule
increases number of sodium potassium transport proteins increases blood pressure
45
effect of ADH on collecting duct
becomes permeable to water
46
filtration occurs in...
the renal corpuscle
47
function of loop of Henle
concentrates solutes in the medulla
48
function of collecting duct
concentrate the urine
49
descending loop of Henle is ______ to water
permeable
50
ascending loop of Henle is ______ to water
impermeable
51
juxtaglomerular apparatus
monitors filtrate pressure in the distal tubule
52
when filtrate pressure is too low...
renin is secreted
53
renin leads to...
angiotensin I travels to lungs to turn into angiotensin II
54
angiotensin II causes...
blood vessels to constrict, raising blood pressure adrenal cortex to release aldosterone
55
aldosterone acts on...
the distal tubule to absorb sodium and secrete potassium to increase blood pressure
56
why does sodium absorption increase blood pressure?
water follows sodium which increase blood volume
57