3. Endocrine System Flashcards
(68 cards)
where are peptide hormones manufactured?
rough ER
anterior pituitary hormones
FSH
LH
ACTH
TSH
prolactin
HGH
posterior pituitary hormones
ADH
oxytocin
where are steroid hormones manufactured?
smooth ER
glucocorticoids of the adrenal cortex
cortisol and aldosterone
gonadal hormones
estrogen, progesterone and testosterone
where are tyrosine derivative hormones manufactured?
enzymes in the cytosol or the rough ER
tyrosine derivative hormones
T3, T4, epinephrine and norepinephrine
epinephrine and norepinephrine action
water-soluble so dissolve in blood and bind to receptors to use cAMP
are hydrophilic hormones fast or slow?
fast
parathyroid hormone
released in response to low calcium in blood
causes increased osteoclast activity
induces excretion of phosphate to keep calcium high
increases calcium uptake in the gut from food
calcitonin
released by C cells in response to elevated calcium in blood
decreases osteoclast activity
glucagon
released by the pancreas (alpha cells) in response to low glucose
insulin
released by pancreas (beta cells) in response to high glucose
cortisol
released from adrenal cortex in response to prolonged stress
glucocorticosteroid - influences glucose mobilization (increase)
aldosterone
released from adrenal cortex to increase water reabsorption in the kidneys due to a mineral depletion (Na and Cl)
salt content remains the same while blood volume rises
mineralocorticoid
ADH
causes collecting ducts of kidneys to become permeable to water
increases blood pressure
decreases urine output
released by posterior pituitary
oxytocin
increases uterine contraction
induces milk ejection
released by posterior pituitray
how does posterior pituitary release hormones?
synthesized in hypothalamus and then transported down
thyroid-stimulating hormone (TSH)
stimulates thyroid to release T3 and T4 using cAMP
adrenocorticotropic hormone (ACTH)
stimulates the adrenal cortex to release glucocorticoids using cAMP
released in response to stress
human growth hormone (HGH)
stimulates all types of growth
prolactin
promotes lactation
inhibited by hypothalamus
T3 and T4
increase the basal metabolic rate
regulated by TSH