5- Integumentary Flashcards
Skin accounts for what percent of body weight
7 %
Thickness of skin
1.5 to 4 mm
epidermis
superficial region, waterproof
dermis
fibrous connective tissue
hypodermis
loose areolar connective tissue and adipose tissue
Skins functions
1- protection 2- body temp 3- excretion (through sweat) 4- vitamin d (produces) 5- sensory receptors
kerationcytes
- produces keratin
- produces antibiotics and enzymes that detoxify harmful chemicals exposed to the skin
- undergo continuous mitosis
- deepest part of epidermis
keratin
tough fibrous protein gives epidermis protection properties
How often do we have new epidermis?
35-45 days
thick skin
- feet and hands
- 5 layers
thin skin
- 4 layers
strata
bed sheets
stratum basale
deepest epidermal layer
single row of cells
tactile epithelial cells or merkel cells
distributed among keratinocytes
associated with sensory nerves and receptors for touch
melanocytes
10-25% cells in stratum basal
spider-shaped
produce melanin
melanin
transfer through spider legs to keratinocytes
creates skin color
Dark- skinned people
darker melanin
more granules
more pigment
NOT more melanocytes
Light-skinned people
melanin is digested by lysosomes
stratum spinosum
mitosis occurs here
thick bundles of intermediate filaments
tension-resisting protein pre-keratin
dendritic cells
star-shaped
police outer body surface using endocytosis and take up antigens
stratum granulosum
1-5 layers of flattened keratinocytes
granular layer
stratum lucidum
in thick skin
transition zone