50/51: Bone Tumors - Mahoney Flashcards Preview

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Flashcards in 50/51: Bone Tumors - Mahoney Deck (52)
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1

best radiologic test to help diagnose bone lesions, including tumors

x-ray

2

when do you do a biopsy?

last step
- do not do if you will not be treating the malignancy or the center of biopsy performance will not be performing biopsy

3

latent

thin sclerotic or radiolucent narrow margin (0.1-1.0 mm), no periosteal reaction, absent soft tissue mass

4

active

wide (2-10 mm) margin, none or mild periosteal reaction, absent soft tissue mass

5

aggressive

wide or poorly defined margin, mild or major periosteal reaction, soft tissue mass present

6

several ill-defined areas of lucency

moth eaten - aggressive

7

ill-defined pattern of lucency caused by many small irregular holes in the bone

permeative - aggressive infection or malignancy

8

geographic lesions

lesion grows slowly, bone has time to retreat and lay down new bone around the lesion

9

lesion grows in fits or starts, periosteum has time to lay down thin shell of new bone before the leion starts another growht sput

lamellate/ onion skin

10

sun burst/ hair on end

periosteum has no time to lay down bone, but sharpey's fibers bevome stretched out perpendicular to bone and then ossify

11

codman's triangle

only the edges of the raised periosteum will ossify - this little bit of ossification forms a small angle with the surface of bone, but not a complete triangle

12

non-metastatic diseases the produce periosteal reactions

HEATHV

hypertrophic pulmonary osteoarthropathy
endosteal hyperostosis
acromegaly
thyroid acropachy
hypervitaminosis A
*** venous stasis

13

what is bone matrix?

substance in bone produced by osteoblasts AND chondroblasts

14

speckled

chondroid matrix

15

cloudy

osseous matrix

16

ground glass

fibrous, cystic lesion producing little or no calcification

17

4 cartilage forming tumors

osteochondroma
solitary enchondroma
chondroblastoma
chondrosarcoma

18

2 bone forming tumors

osteoid osteoma and osteoblastoma
osteogenic sarcoma

19

benign tumors

enchondroma
osteochondroma
osteoid osteoma
osteoblastoma
giant cell tumore (10% malignant)
chondroblastoma

20

malignant tumors

osteogenic sarcoma
chondrosarcoma
fibrosarcoma
ewing's sarcoma
metastatic carcinoma

21

FOG MACHINES

solitary lytic lesions of bone

Fibrous dysplasia
Osteoid osteoma/osteoblastoma
Giant cell tumor

Metastasis, myeloma
Aneurysmal bone cyst
Chondroblastoma, chondromyxoid fibroma
Hyperparathyroidism, hemangioma
Infection
Non-ossifying fibroma
Eosinophilic granuloma, enchondroma
Solitary boe cyst, sarcoidosis

22

long lesion in a long bone

fibrous dysplasia or non-ossifying fibroma (moves into marrow space)

23

hurts like a b and tough to see

osteoid osteoma
- night pain relieved by ASA or NSAIDS
- produces high amounts of prostaglandins

24

at the end of a long fast, teens have a blast

osteoblastoma
- most common tumor in teens at the ends of the long bones

25

osteoid osteoma v osteoblastoma

no surrounding reactive bone sclerosis in osteoblastoma

26

massive in metaphysis

giant cell tumor

27

most common primary bone malignancy in body

metastasis/myeloma

28

metastasis to bone

adult male - lung
adult female - breast
also kidney and thyroid

29

#1 primary metastasis to foot and ankle bone

colorectal CA

30

most common primary malignatnt tumor of bone in body

myeloma