Heme/Onc

Question 1

actinic keratosis precursor for

Answer 1

SCC

Question 2

Dx criteria for polycythemia vera

Answer 2

1) incr red cell mass
2) NL PaO2
3) splenomegaly

Question 3

Tx of hypercalcemia of malignancy

Answer 3

NS then IV pamidronate

Question 4

MC initial sx of Hodgkin lymphoma

Answer 4

painless lymphadenopathy

Question 5

Hb and Hct for polycythemia vera

Answer 5

Hb > 18

Hct > 52

Question 6

when to biopsy a cervical LN

Answer 6

LN > 3 cm
supraclavicular
night sweats or weight loss

Question 7

Tx multiple myeoma if symptomatic and

Answer 7

autologous stem cell transplant

Question 8

tx multiple myeloma if not indicated for SC transplant

Answer 8

melphan and prednisolone w/ or w/o thalidomide

Question 9

threshold for prophylactic platelet transfusion

Answer 9

plt less than 50,000

Question 10

dx multiple myeloma

Answer 10

bone marrow shows >10% plasma cells

Question 11

typical serum IgG of multiple myeloma

Answer 11

> 3 g/dL

Question 12

what happens about a week after iron replacement for iron deficiency anemia

Answer 12

reticulocytosis

Question 13

differential for hyper segmented PMNs

Answer 13

B12 deficiency

pernicious anemia

Question 14

IDA RDW and MCV

Answer 14

RDW high

MCV normal to low

Question 15

thalasemia trait RDW and MCV

Answer 15

RDW normal

MCV low

Question 16

labs suggestive of hemolysis

Answer 16

incr LDH
decr haptoglobin
incr indirect bili

Question 17

IgM spikes and Bence Jones proteins

Answer 17

Waldenstrom macroglobulinemia

Question 18

low MCV

normal RDW

Answer 18

thalassemia

Question 19

which head and neck lymph nodes are most likely to be malignant if enlarged

Answer 19

supraclavicular

Question 20

MDS MCV

Answer 20

high (macrocytic anemia)