Mom - Random Stuff Flashcards

1
Q

Intranuclear inclusions seen in herpes simplex encephalitis

A

Coronary typeA inclusions

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2
Q

Cytoplasmic inclusions pathognomonic of rabies

A

Negri bodies

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3
Q

Neuronal inclusions characteristic of Parkinson disease

A

Lewy bodies

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4
Q

Cytoplasmic inclusions bodies associated with aging

A

Lipofascial granules

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5
Q

Dark cytoplasmic pigment in neurons of the substantia nigra and locus coeruleus, not seen in patients with Parkinson disease

A

PD2 loss of melanin

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6
Q

Eosinophilic, rod-like inclusions in hippocampus of

Alzheimer patients

A

Hirano bodies

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7
Q

Diagnostic of Alzheimer disease

A

Newofibrillary plaques and tangles

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8
Q

Filamentous inclusions that stain with silver, do not survive neuronal death

A

Pick bodies

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9
Q

Filamentous inclusions that stain with PAS and ubiquitin

A

Lewy bodies

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10
Q

B1 (thiamine)

A

Decarboxylation of alpha-keto acids (carbohydrate metabolism)

  • -Beriberi (peripheral neuropathy, heart failure)
    • Wernnicke-Korsakoff syndrome
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11
Q

B2 (riboflavin)

A

Mitochondrial electron carrier (FMN, FAD)

  • -Angular cheilosis, stomatitis, glossitis
  • Normocytic anemia
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12
Q

B3 (niacin)

A

Electron transfer reactions (NAD/NADP)

    • Pellagra (dermatitis, dementia, diarrhea)
  • -Peripheral neuropathy
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13
Q

B6 (pyridoxine)

A

Transamination of amino acids (amino acid synthesis)

–Cheilosis, stomatitis, glossitis

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14
Q

B9 (folate, folic acid)

A

Hydroxymethyl/formyl carrier (purine & thymine synthesis)

    • Megaloblasic anemia
    • Neural tube defects (fetus)
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15
Q

B12 (cobalamin)

A

Isomerase & methyltransferase cofactor (DNA & methionine synthesis

    • Megaloblasic anemia
    • Neurologic deficits
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16
Q

C (ascorbic acid)

A

Hydroxylation of proline & lysine (collagen synthesis)

–Scurvy

17
Q

Ventromedial

A

Mediates satiety; destruction leads to hyperphagia

18
Q

Lateral

A

Mediates hunger; destruction leads to anorexia

19
Q

Anterior

A

Mediates heat dissipation; destruction leads to hyperthermia

20
Q

Posterior

A

Mediates heat conservation; destruction leads to hypothermia

21
Q

Arcuate

A

Secretion of dopamine (inhibits prolactin), growth hormone-releasing hormone & gonadotropin-releasing hormone

22
Q

Paraventricular

A

Antidiuretic hormone, corticotropin-releasing hormone, oxytocin & thyrotropin-releasing hormone secretion

23
Q

Supraoptic

A

Secretion of antidiuretic hormone & oxytocin

24
Q

Suprachiasmatic

A

Circadian rhythm regulation & pineal gland function